Low‐Level Laser Therapy in the Treatment of Mucous Membrane Pemphigoid: A Promising Procedure

Abstract

The results reported in this case show that the healing of mucous membrane pemphigoid was achieved when LLLT was used as an adjunct to the application of a local corticosteroid.

Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus: a prospective case series

“…Some recent evidence suggests that LLLT would currently appear to be a possible treatment for some patients with different type of oral erosive lesions, guaranteeing an immediate and notable analgesic effect [8][9][10][11][12][13][14]. In particular, in a preliminary report our group reported that LLLT appeared to be a possible treatment for some patients with OLP and can be used as an alternative therapy alongside standard treatment methods, especially for unresponsive patients [13].…”

“…To date, few reports have been published describing the efficacy of laser irradiation in erosive oral mucosal diseases, such as mucous membrane pemphigoid [8][9][10], aphthous stomatitis [11,12], OLP [13] and chronic lichenoid graft-vs.-host disease [14].…”

Mucous Membrane Pemphigoid

“…24 IVIG as monotherapy led to complete resolution of the symptoms and the laryngeal lesions without any side-effects. 94 Failure of IVIG to control MMP is also reported. 95 …”

Mucous membrane pemphigoid: A wide-ranging assessment of various cases and corresponding methods of diagnosis and treatment

“…Lastly, the comprehensive diversity of treatment options discussed, including various subtypes, multiple levels of severity and unique genetic anomalies. This has proven that technological advances in medicine have been able to provide innovative treatments, including the diode laser, LLLT, Hsp90, mini-scleral lenses and entropion repairs, in response to the increasing awareness of MMP [34,37,38]. With the combination of multiple medical professions, including dentists, dermatologists, ophthalmologists, and head and neck specialists, a collaboration of physicians could bring awareness and reduce the delay in diagnosing MMP.…”

“…Factors that play significant roles to treating MMP by using LLLT include dose, wavelength, and the energy amount applied. With these facts noted, it is suggested that this technique could be a beneficial way to treat MMP, yet there are no clinical trials proceeding to prove this method [38]. Upon learning about this method, we hope more of LLLT related clinical trials could be approved for experimentation purposes as it is important to avoid severe side effects that the drugs can potentially cause a patient.…”