2022
DOI: 10.3889/oamjms.2022.7428
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Low Level Laser versus Platelet-rich Plasma in Treatment of Alopecia Areata: A Randomized Controlled Intra-patient Comparative Study

Abstract: Background: Non-scarring alopecia areata (AA) is a disease that is mediated through autoimmunity. Recently, autologous platelet-rich plasma (PRP) and photobiomodulation (PBM), commonly known as low-level laser (or light, LLLT) have been suggested to provide a valuable role in stimulating the growth of hair follicles (HF) Aim: Compare between the significance and wellbeing of PRP and LLLT in the management of AA. Patients & methodology: Thirty patients, each having three patches of AA par… Show more

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Cited by 5 publications
(5 citation statements)
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“…Efficacy of PRP in AA has also been compared to topical minoxidil and low-level laser therapy (LLLT). PRP showed superior to 5% topical minoxidil in improving dystrophic hair and had a greater effect on improving hair diameter compared to LLLT ( 34 , 43 ).…”
Section: Resultsmentioning
confidence: 98%
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“…Efficacy of PRP in AA has also been compared to topical minoxidil and low-level laser therapy (LLLT). PRP showed superior to 5% topical minoxidil in improving dystrophic hair and had a greater effect on improving hair diameter compared to LLLT ( 34 , 43 ).…”
Section: Resultsmentioning
confidence: 98%
“…At the full-text stage, 87 full articles met our predefined selection criteria, and we further excluded 55 publications for the following reasons: review articles ( n = 27), conference abstracts ( n = 17), wrong population ( n = 5), wrong intervention ( n = 3), commentary articles ( n = 3), and secondary cicatricial alopecias ( n = 2) ( Figure 1 ). Thirty-two studies were included: 11 randomized controlled trials (RCTs) ( 33 43 ), 4 non-randomized studies ( 44 47 ), and 17 case series or case reports ( 48 64 ). Between 2013 and 2022, 23 AA studies ( 33 55 ) and nine PCA studies ( 56 64 ) were included, totaling 621 patients with AA and 19 with PCAs.…”
Section: Resultsmentioning
confidence: 99%
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