Low Skin Temperatures Produced by New Skin Refrigerants

Abstract

Temperatures produced by Cryosthesia -30 degrees C, Cryosthesia -60 degrees C, and Frigiderm were measured in minipigs. Cryosthesia -60 degrees C and Cryosthesia -30 degrees C were both found to rapidly lower skin temperatures to levels that have been shown to cause cell injury, necrosis, and loss of melanocytes. Use of these agents requires extreme caution in dermabrasion.

A Histologic Evaluation of the Effects of Skin Refrigerants in an Animal Model

“…Additional studies of Freon ‐ 12 and Freon ‐12‐based skin refrigerants have been reported by Strick and Moy 10 and Dzubow 11 . The sequence of events that led to these studies as well as our own has been discussed by Alt in a recent publication 1…”