Lower cortical thickness and increased brain aging in adults with cocaine use disorder
David Schinz,
Benita Schmitz-Koep,
Marlene Tahedl
et al.
Abstract:BackgroundCocaine use disorder (CUD) is a global health issue with severe behavioral and cognitive sequelae. While previous evidence suggests a variety of structural and age-related brain changes in CUD, the impact on both, cortical thickness and brain age measures remains unclear.MethodsDerived from a publicly available data set (SUDMEX_CONN), 74 CUD patients and 62 matched healthy controls underwent brain MRI and behavioral-clinical assessment. We determined cortical thickness by surface-based morphometry us… Show more
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