Lower Urinary Tract Symptoms in a prospective cohort of COVID-19 survivors

Abstract

Purpose:To analyze the prevalence of lower urinary tract symptoms (LUTS) in patients who survived moderate and severe forms of COVID-19 and the risk factors for LUTS six months after hospitalization. Materials and Methods:In this prospective cohort study, patients were evaluated six months after hospitalization due to COVID-19. LUTS were assessed using the International Prostate Symptom Score. General health was assessed through the Hospital Anxiety and Depression Scale and the EQ5D-L5 scale, which evaluates mobility, ability to perform daily activities, pain and discomfort and completed a self-perception health evaluation.Results: Of 255 participants, 54.1% were men and the median age was 57.3 [44.3 -66.6] years. Pre-existing comorbidities included diabetes (35.7%), hypertension (54.5%), obesity (30.2%) and physical inactivity (65.5%). One hundred and twenty-four patients (48.6%) had a hospital stay >15 days, 181 (71.0%) were admitted to an ICU and 124 (48.6%) needed mechanical ventilation.Median IPSS was 6 [3-11] and did not diff er between genders. Moderate to severe LUTS aff ected 108 (42.4%) patients (40.6% men and 44.4% women; p=0.610). Nocturia (58.4%) and frequency (45.9%) were the most prevalent symptoms and urgency was the only symptom that aff ected men (29.0%) and women (44.4%) diff erently (p=0.013). LUTS impacted the quality of life of 60 (23.5%) patients with women more severely aff ected (p=0.004). Diabetes, hypertension, and self-perception of worse general health were associated with LUTS.Conclusions: LUTS are highly prevalent and bothersome six months after hospitalization due to COVID-19. Assessment of LUTS may help ensure appropriate diagnosis and treatment in these patients.

MRI and biopsy in prostate cancer are the hot topic in this number of International Brazilian Journal of Urology

“…Dr. Gomes and collegues from Brazil performed in page 287 ( 3 ) an interesting study about theurinary tract symptoms in a prospective cohort of COVID-19 survivors and concluded that LUTS are highly prevalent and bothersome six months after hospitalization due to COVID-19. Assessment of LUTS may help ensure appropriate diagnosis and treatment in these patients.…”