2024
DOI: 10.1111/aas.14392
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Lower versus higher blood pressure targets in comatose patients resuscitated from out‐of‐hospital cardiac arrest—Protocol for a secondary Bayesian analysis of the box trial

Johannes Grand,
Sebastian Wiberg,
Jesper Kjaergaard
et al.

Abstract: BackgroundThe management of blood pressure targets during intensive care after out‐of‐hospital cardiac arrest (OHCA) remains a topic of debate. The blood Pressure and Oxygenation Targets After OHCA (BOX) trial explored the efficacy of two different blood pressure targets in 789 patients during intensive care after OHCA. In the primary frequentist analysis, no statistically significant differences were found for neurological outcome after 90 days.MethodsThis protocol outlines secondary Bayesian analyses of 365‐… Show more

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