Loxosceles spider bite in Turkey (Loxosceles rufescens, Sicariidae, Araneae)

Yiğit, Nazife; Bayram, Abdullah; Ulasoglu, D.; Danişman, Tarık; Öcal, İlkay Çorak; Sancak, Zafer

doi:10.1590/s1678-91992008000100016

Cited by 19 publications

(20 citation statements)

References 14 publications

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“…The severity of loxoscelism depends on a number of factors. These include: the amount of venom injected, the type of venom injected (the degree of sphingomyelinase D activity), the sex of the spider (female spiders are known to have more toxic venom), the site of the bite and the host's reaction to the venom 10 15 19…”

Section: Discussionmentioning

confidence: 99%

Rare case of dermonecrosis caused by a recluse spider bite in Europe

et al. 2016

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Spider poisoning is rare in Europe, with very few reported cases in the literature. Recluse spider (genus Loxosceles) bites may lead to cutaneous and systemic manifestations known as loxoscelism. We report the second known case of spider bite poisoning in Malta caused by Loxosceles rufescens (Mediterranean recluse spider). A young adult female presented with localised erythema and pain on her left thigh after a witnessed spider bite. Over a few days, the area developed features of dermonecrosis together with systemic symptoms, including fever, fatigue and a generalised erythematous eruption. She was managed by a multidisciplinary team and the systemic symptoms resolved within 6 days, while the skin lesion healed with scarring within 2 months. A recluse spider bite should be considered in patients with dermonecrosis. Although spider bite poisoning is uncommon in Europe, it is important to diagnose and manage it appropriately since it could lead to potentially serious sequelae.

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Section: Discussionmentioning

confidence: 99%

Rare case of dermonecrosis caused by a recluse spider bite in Europe

et al. 2016

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“…Published reports have been identified in the Eastern Mediterranean Basin (e.g. Israel: Cohen et al, 1999; Davidovici et al, 2006; Greece: Stefanidou et al, 2006; Turkey: Akdeniz et al, 2007; Yigit et al, 2008) while fewer come from the Western Mediterranean Basin (e.g. Spain: de Entrambasaguas et al, 2007; France: Pernet et al, 2010; Italy: Ribuffo et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Not as docile as it looks? Loxosceles venom variation and loxoscelism in the Mediterranean Basin and the Canary Islands

Planas

Zobel-Thropp

Ribera

et al. 2015

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The medical importance of Loxosceles spiders has promoted extensive research on different aspects of their venoms. Most of the reported cases of loxoscelism have occurred in the Americas, and thus, much work has focused on North and South American Loxosceles species. Interestingly, loxoscelism cases are rare in the Mediterranean Basin although Loxosceles rufescens, endemic to the Mediterranean, is an abundant spider even in human-altered areas. Thus, it has been suggested that the venom of L. rufescens could be of less medical relevance than that of its congeners. In this study, we challenge this hypothesis by using multiple approaches to study venom variation in selected species and lineages from the Mediterranean Basin and the Canary Islands. We found that SMase D activity, the key bioactive component of Loxosceles venom, is comparable to American species that are confirmed to have medically relevant bites. The venom protein composition using SDS-PAGE presents some differences among regional Loxosceles taxa in banding pattern and intensity, mostly between the Canarian and L. rufescens lineages. Differences between these species also exist in the expression of different paralogs of the SicTox gene family, with the Canarian species being less diverse. In conclusion, our results do not support the challenged hypothesis, and suggest that venom of these species may indeed be as potent as other Loxosceles species. Pending confirmation of loxoscelism with direct evidence of Loxosceles bites with species identification by professionals, Loxosceles in the Mediterranean region should conservatively be considered medically relevant taxa.

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“…There is no diagnostic test available to quickly help the physician make a diagnostic or therapeutic decision, but a rapid diagnosis is crucial for satisfactory treatment [7], [12]. In the present paper, a case, which we presumed to be due to the bite of Loxosceles rufescens, is evaluated in the light of literature [13], [14], [15], [16], [17], [18], [19], [20], [21].…”

Section: Introductionmentioning

confidence: 99%

Local Dermonecrosis with Generalized Urticaria Probably Due to Loxosceles rufescens Bite

Charitos

Pennisi

Lepore

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: The spiders of the Loxosceles genus, commonly denoted as “brown spiders” or “Mediterranean recluse” or “brown recluse,” belong to the spider family Sicariidae, suborder Labidognatha, order Araneida, class Arachnida, and phylum Arthropoda. This spider is widespread in Africa and South/Central America, but it is also distributed in North America, in the West Indies, in the Mediterranean Europe, and in China. CASE REPORT: Here, we report the case of a severe dermonecrotic loxoscelism identified in Southern Italy, probably due to the bite of Loxosceles rufescens. The patient was a women admitted at hospital ER because of a little skin erythema that evolved toward a severe necrosis and ulceration within 20 days. After clinical and laboratory data excluded other local and systemic diseases, she was treated with a systemic and local therapy using corticosteroids and antibiotics with the diagnosis of loxoscelism. The healing from the local skin lesion occurred within 2 months, but the local pain, weakness, and discomfort lasted for a long time. CONCLUSION: It is the fisrt time that a possible case of systemic loxoscelism with skin generalized urticaria is reported in Italy.

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Loxosceles spider bite in Turkey (Loxosceles rufescens, Sicariidae, Araneae)

Cited by 19 publications

References 14 publications

Rare case of dermonecrosis caused by a recluse spider bite in Europe

Rare case of dermonecrosis caused by a recluse spider bite in Europe

Not as docile as it looks? Loxosceles venom variation and loxoscelism in the Mediterranean Basin and the Canary Islands

Local Dermonecrosis with Generalized Urticaria Probably Due to Loxosceles rufescens Bite

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