<b>DEVELOPMENTAL CHANGES IN THE ACTIVITY OF GLUTATHIONE <i>S</i>-TRANSFERASE AND ITS IMMUNOCYTOCHEMICAL LOCALIZATION IN THE HYPOPLASTIC CEREBELLUM OF JAUNDICED GUNN RATS</b>

Abstract

Developmental changes in the activity of glutathione S-transferase (GST) and its immunocytochemical localization were studied in the cerebella of homozygous (j/j) and heterozygous (j/+) Gunn rats. The activity of jaundiced j/j rats began to increase after 8 days of life and reached twice as high as that of non-jaundiced j/+ rats at 15-20 days, chronologically coincident with the development of bilirubin