&lt;b&gt;Optical density evaluation around the zirconia granules used as graft in rat calvaria

Farinazzo, Carolina Silva; Iwaki, Lílian Cristina Vessoni; Filho, Liogi Iwaki; Takeshita, Wilton Mitsunari; Silva, Mariliani Chicarelli da; Cândido, Graciela Cristina

doi:10.4025/actascihealthsci.v36i2.19275

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…11,12 Quantitation of optical density (OD) has been utilized in both clinical and research environments. [13][14][15][16][17][18] The methods employed ultimately provide a value for OD in a given region of interest (ROI). This has been achieved using two primary methodologies, which have allowed comparison of OD across multiple radiographic images while controlling for factors that may influence the results, such as exposure factors.…”

Section: Introductionmentioning

confidence: 99%

Qualitative and Quantitative Radiological Measures of Fracture Healing

Field¹,

Ruthenbeck²

2018

Vet Comp Orthop Traumatol

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The formulation of appropriate postoperative strategies, following fracture repair, currently involves an understanding of radiological and clinical outcome measures. This study has evaluated several modalities used to assess the progression of bone healing in a sheep tibial segmental defect model. Measures of defect optical density and volumetric data including bone density (BD), bone volume (BV) and bone mass (BM) were compared with qualitative data involving visual appraisal of radiographs [% bridging callus and modified radiographic union score tibia (mRUST)] and a clinical outcome measure (locomotory function). Percent bridging callus and mRUST measures displayed strong correlation ( = 0.999), while locomotory function was weakly correlated with bridging callus ( = 0.029) and mRUST ( = 0.046). There was moderate to strong correlation between the qualitative and quantitative data. Bone density, BV and BM showed strong correlations within this dataset (BD-BV, = 0.814; BD-BM, = 0.818; BV-BM, = 1.000). Likewise, optical density measures were strongly correlated with BD ( = 0.824), BV ( = 0.957) and BM ( = 0.959). The utilization of both qualitative and quantitative data, in assessment of the progression of fracture healing, has provided valuable insight. Measures of optical density have been shown to make a substantial contribution to this assessment and which should be considered for use in studies evaluating fracture healing.

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