2014
DOI: 10.2169/internalmedicine.53.2247
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<i>Pseudomonas stutzeri</i> Necrotizing Pneumonia in Pre-existing Pulmonary Tuberculosis

Abstract: Pseudomonas stutzeri (P. stutzeri) is a Gram-negative, non-fermenting rod. It is a rare pathogen; therefore, its isolation is often associated with colonization or contamination. We herein describe the first reported case of necrotizing pneumonia caused by P. stutzeri in a non-HIV infected patient with previously undiagnosed pulmonary tuberculosis. The isolate was found to be antibiotic resistant, which led to the failure of the initial treatment. This case highlights the unique presentation of necrotizing pne… Show more

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Cited by 7 publications
(5 citation statements)
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“…Four patients were successfully treated with antibiotics and/or surgery; however, the source of infection could not be identified. Late Prosthetic valve endocarditis was documented in Shalabi et al and Rosenberg et al cases [4,6]. An indolent clinical course was also well documented in the Grimaldi et al case with relapse after four years [8].…”
Section: Discussionmentioning
confidence: 84%
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“…Four patients were successfully treated with antibiotics and/or surgery; however, the source of infection could not be identified. Late Prosthetic valve endocarditis was documented in Shalabi et al and Rosenberg et al cases [4,6]. An indolent clinical course was also well documented in the Grimaldi et al case with relapse after four years [8].…”
Section: Discussionmentioning
confidence: 84%
“…It has been reported to cause pneumonia, meningitis, ocular infection, bacteremia, osteomyelitis and joint infections [1][2][3]. In addition, it has also been isolated as an opportunistic pathogen [2,4]. Interestingly, most cases of infection due to P. stutzeri have been reported from the Mediterranean Basin, suggesting that geographical factors [3].…”
Section: Discussionmentioning
confidence: 99%
“…As well, this patient had a preceding CNST infection, which raises the possibility of the P. stutzeri infection opportunistically developing in the setting of previous broad spectrum antimicrobial treatment, as is often the case with Pseudomonas aeruginosa [11]. Additionally, a recent case of a necrotizing pneumonia caused by P. stutzeri developed in a patient with pulmonary tuberculosis [12] and was hypothesized to have been facilitated by parenchymal destruction caused by Mycobacterium tuberculosis . This supports the notion that P. stutzeri infection may develop in previously inflamed or infected tissue, although no rigorous data investigating this hypothesis is available.…”
Section: Discussionmentioning
confidence: 85%
“…To date, many cases of P. stutzeri infection have been reported in the literature, including bacteremia, pneumonia, osteomyelitis, arthritis, and ocular infections [ 6 , 8 ]. It has also been hypothesized that P. stutzeri infections may develop more easily in inflamed tissue, as was observed in two patients being treated for pulmonary tuberculosis with considerable parenchymal destruction who developed complicating superinfections with P. stutzeri [ 9 , 10 ].…”
Section: Discussionmentioning
confidence: 99%