<p>Comparison of Extraction Socket Healing in Non-Diabetic, Prediabetic, and Type 2 Diabetic Patients</p>

Abstract

Objective: To compare the healing of extraction socket among non-diabetic, prediabetic, and diabetic patients. Materials and Methods: A single-center prospective observational study was conducted. Glycated hemoglobin and random blood glucose were recorded for all the participants before the procedure. A trained and calibrated examiner evaluated the socket size on postoperative days 0 and 7. Postoperative pain (PoP), discharge, swelling, infection, erythema, dry socket, and the number of analgesics were also recorded. Results: A total of 100 participants completed this study with a mean age of 54.7±12.11. There was no significant difference in the mean socket size among the three study groups on day 0 (P=0.101). However, there was a significant difference in the mean socket size on day 7 among the three groups. A post hoc test showed that the diabetic group had a larger socket size than the non-diabetic group (P=0.011). Complications like swelling and infection were more in the diabetic group. There was no significant difference in the mean number of analgesics among the three groups (P=0.169). The adjusted means for the socket size on postoperative day 7 was significantly higher for diabetic than the non-diabetic group. Conclusion: The socket dimension was larger on postoperative day 7 in people with diabetes which suggested delayed healing without persistent complications. Dental extractions can be performed safely in optimally controlled diabetic patients with minimal complications.

The Effect of Coenzyme Q10/Collagen Hydrogel on Bone Regeneration in Extraction Socket Prior to Implant Placement in Type II Diabetic Patients: A Randomized Controlled Clinical Trial

“…Management of diabetic patients is often challenging for the Oral and Maxillofacial surgeons due to the impaired healing of the dental sockets after tooth extraction. Although the incidence of complications as post-operative infections and delayed healing is minimal in optimally controlled diabetic patients, there would still be some risk [ 4 ]. Thus, in this study, controlled diabetic patients have been chosen to be treated in a way to permit the chance for further rehabilitation by means of removable or fixed restorations.…”

“…The healing of the extraction socket leads to horizontal and vertical alveolar ridge resorption that can make implant placement difficult or affect the functional and aesthetic outcomes [ 3 ]. Multiple factors play role in bone resorption after tooth extraction including the number of teeth extracted, bone density, infection, or hormonal dysregulation including that associated with diabetes mellitus [ 4 ].…”

Prevalence of Diabetes and Impaired Fasting Glycemia in Patients With Oral Cancer: A Retrospective Study in Hungary

“…People living with diabetes often experience xerostomia (15) and burning mouth syndrome (16), which usually lead to tasting dysfunctions (17). After oral surgeries, delayed wound healing can cause complications, such as dry sockets (18). Geographic tongue (19), lichen planus (20), and oral candidiasis (21) are more common among people with DM (22).…”

Extrações dentárias em pacientes com diabetes mellitus: estudo retrospectivo

“…Nossos resultados evidenciaram baixa ocorrência (2,8%) de complicações após exodontias em pacientes com DM1 e DM2. Estudos realizados em pacientes com DM sujeitos a exodontias mostraram que a taxa de infecção após extrações dentárias no sítio cirúrgico variou de 2,5% a 8,33% (Aronovich et al, 2010;Motta et al, 2013;Power et al, 2019;Gadicherla et al, 2020). Autores observaram uma taxa de 1,4% (25/1821) de infecção pós-operatória após extração dentária em uma clínica odontológica universitária e enfatizaram que a prescrição de antibióticos não teve influência significativa na prevenção de infecção pós-operatória (Yue Yi et al, 2021).…”

“…Estudos prospectivos têm sugerido que não há diferença estatisticamente significativa nos resultados de complicações após exodontias em pessoas com e sem diabetes, mas são escassos os estudos que se propõem a comparar a taxa e o tipo de complicação após exodontia entre pacientes com DM1 e DM2 (Aranovich et al, 2010;Fernandes et al, 2015;Power et al, 2019;Gadicherla et al, 2020).…”