&lt;title&gt;Computerized video-enhanced high temporal resolution of erythrocytes sedimentation rate (ESR-graphy) reveals complex dynamic and self-organizing properties of whole blood&lt;/title&gt;

Воейков, В.Л.; Кондаков, С. Э.; Buravleva, E. V.; Kaganovsky, I.; Reznikov, M.

doi:10.1117/12.387143

Cited by 6 publications

(9 citation statements)

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“…2 In general, the results obtained correlate well with the measurements done by temporalresolved photometry. 6,15 Oscillations in the sedimentation rate of the red blood/plasma boundary occur in a rather regular manner with about one oscillation (max and min) per minute (see Fig. 5).…”

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 97%

“…This means that the red blood pillar may overcome the force of gravity. 6,15 The boundary drops at a fairly constant rate (0.7 -4 mm/hour depending on donor, dilution, and agent addition), but eventually this smooth movement is interrupted by a sudden fall. Because an OCT A-scan capture time is about 1 second, such a transition of sedimentation rate occurs within one second.…”

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 98%

“…Such energy released due to oxidative reactions in whole blood may be absorbed by HbO 2 molecules and their clusters in erythrocytes providing for oxygen release. 6,15 Boundary oscillations may indicate that cyclic processes of oxygen consumption and its utilization by cells are manifested in a coordinated manner.…”

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 99%

“…6,15 According to this hypothesis blood is considered as a colloid system with unusual properties such as showing a solution of two or more water soluble polymer species (i.g., dextran and polyethylene glycol), in which phase separation may occur if relative concentrations of both solutes reach certain critical values. Such solutions usually contain only a few percent of polymers, but in different proportions.…”

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 99%

“…5,6 Clinical applications of the ESP are based on the facts that RBC can be lighter than normal, for instance due to iron deficiency, will settle more slowly than normal cells; RBC concentration can be different, what changes the interaction between the cells and they fall down slowly (polycythaemia -an excess of RBC) or faster (anaemia -a deficiency of RBC); and many exogenous or endogenous macromolecules can change the aggregation properties of blood 7-9 -the aggregated RBC fall down faster. 5 For example, improved nutrition causes the decreasing of ESR, elevation of the blood urea accelerates the ESR, cholesterol increases ESR, whereas lecithin decreases it.…”

Section: Introductionmentioning

confidence: 98%

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<title>Blood immersion and sedimentation study using OCT technique</title>

Tuchin

Wang

2001

SPIE Proceedings

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The refractive index matching (immersion) method is used to enhance the optical penetration depth of whole blood in in vitro study by the NIR optical coherence tomography (OCT) technique. It was found that for tested agents (glucose, dextrans, propylene glycol, and trazograph) the enhancement of penetration was from 20 % to 150 %. In the blood sedimentation study, regular or irregular oscillations or jumps of the RBC/plasma boundary were observed. The oneminute time period of regular oscillations correlated well with the kinetics of the aggregation process. For the first time OCT images of blood aggregates in a small plastic vessel were observed. Presented results have potentials in intravascular OCT imaging and in blood sedimentation and aggregation studies for diagnostic purposes.

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Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 97%

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 98%

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 99%

Section: The Oscillatory Nature Of Blood Sedimentationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

See 3 more Smart Citations

<title>Blood immersion and sedimentation study using OCT technique</title>

Tuchin

Wang

2001

SPIE Proceedings

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Heterogeneity of hypoxia in solid tumours and mechanochemical reactions with oxygen nanobubbles

2017

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Effect of red blood cell aggregation and sedimentation on optical coherence tomography signals from blood samples

Kirillin¹,

Priezzhev²,

Tuchin³

et al. 2005

J. Phys. D: Appl. Phys.

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In this work, Monte Carlo simulation is used to obtain model optical coherence tomography (OCT) signals from a horizontally orientated blood layer at different stages of red blood cell (RBC) aggregation and sedimentation processes. The parameters for aggregating and sedimenting blood cells were chosen based on the data available from the literature and our earlier experimental studies. We consider two different cases: a suspension of washed RBCs in physiological solution (where aggregation does not take place) and RBCs in blood plasma (which provides necessary conditions for aggregation). Good agreement of the simulation results with the available experimental data shows that the chosen optical parameters are reasonable. The dependence of the numbers of photons contributing to the OCT signal on the number of experienced scattering events was analysed for each simulated signal. It was shown that the maxima of these dependences correspond to the peaks in the OCT signals related to the interfaces between the layers of blood plasma and blood cells. Their positions can be calculated from the optical thicknesses of the layers, and the absorption and scattering coefficients of the media.

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<title>Computerized video-enhanced high temporal resolution of erythrocytes sedimentation rate (ESR-graphy) reveals complex dynamic and self-organizing properties of whole blood</title>

Cited by 6 publications

References 0 publications

<title>Blood immersion and sedimentation study using OCT technique</title>

<title>Blood immersion and sedimentation study using OCT technique</title>

Heterogeneity of hypoxia in solid tumours and mechanochemical reactions with oxygen nanobubbles

Effect of red blood cell aggregation and sedimentation on optical coherence tomography signals from blood samples

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