Luminal, Its Toxic Effects

Abstract

infiltrated with small, grayish-white, firm areas from 1 to 3 mm. in diameter. No evidence of pneumonia, or cavities. Right pleural sac showed old adhesions throughout. Light lung, 1,25o gm.; identical with left. Pericardial sac contained some excess of clear, yellow Quid. Serous surfaces apparently normal. Heart and aorta not opened. Mesenteric group apparently normal, except for one lymph-node, which was moderately enlarged, caseous and calcified. Brain and spinal cord not examined. (Permission for partial necropsy only was obtained.) Histologie Examination.-Spleen: Except in a few places the follicular arrangement of the tissues was lost, (¡encrai lymphoid hyperplasia prosent. There were many large, fairly well-circumscribed areas of lymphoid and polynuclear cells together with round, yeast-like bodies, many of which were cndosporulnting. In places marked congestion. There were a few nccrotie areas. Trabecuhie were indistinct. Liver: .Moderate, cloudy swelling present. Numerous small lymphocytic and polynuclear cell-collections noted, chielly in the lobular tissues. Some of these contained the above-mentioned bodies. There was an area with a giant-cell which closely resembled a milhiry tubercle. Pancreas: Moderate congestion and a few areas of necrosis. There were a few small cellular masses similar to liver. Kidneys: Cortical epithelium showed degeneration and ilcsqiiamative changes-some cloudy swelling but chielly fatty degeneration. There were several large and small cellular collections witli and without yeast-like bodies similar to spleen and liver. There was an area with a giant-cell which closely resembled a. miliary tubercle. Adrenal: A few of the larger medullary arteries contained thrombi. A few small, cortical, cellular collections with bodies. Mesenteric Lymph-Node: Capsule fibrotic and hyalinized. Lymphoid tissues almost completely nccrotie and in places calcified. There were no giant-cells or other cellular evidences of tuberculosis. I.ungs: Moderate fibrosis of pleura. Moderate emphysema. Many large areas contained cells and bodies similar to spleen.