Lung-Resident Memory CD8<sup>+</sup> T Cells in Human Influenza: How Innate Are They?

Nguyen, Thi H. O.; Kedzierska, Katherine

doi:10.1164/rccm.202106-1508ed

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Nonhuman Primate and Human Challenge Models1

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2024

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“…Chiu presented data from CHIM studies on RSV and influenza virus [14,26], showcasing the enrichment of tissue-resident T cells in the lower respiratory tract and their correlation with reduced severity of disease and reduced viral load. Omics technologies were essential to analyze differentially expressed gene pathways in tissue-resident T cells, demonstrating the production of chemokines and cytokines typically associated with innate immunity.…”

Section: Nonhuman Primate and Human Challenge Modelsmentioning

confidence: 99%

Scientific highlights of the 9th ESWI Influenza Conference

Reperant,

Russell,

Osterhaus

2024

One Health Outlook

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The European Scientific Working Group on Influenza (ESWI) held the 9th ESWI Influenza Conference in Valencia from 17—20 September 2023. Here we provide a summary of twelve key presentations, covering major topics on influenza virus, respiratory syncytial virus (RSV) and SARS coronavirus 2 (SARS-CoV-2) including: infection processes beyond acute respiratory disease, long COVID, vaccines against influenza and RSV, the implications of the potential extinction of influenza B virus Yamagata lineage, and the threats posed by zoonotic highly pathogenic avian influenza viruses.

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Section: Nonhuman Primate and Human Challenge Modelsmentioning

confidence: 99%