Lung transplantation for <scp>post‐COVID</scp>‐19 pulmonary fibrosis

Gogia, Pratibha; Attawar, Sandeep; Singh, Vivek; Bhatnagar, Tarun; Sharma, Sanjay; Batra, Khushboo; Khare, Swapnil

doi:10.1002/rcr2.862

Cited by 8 publications

(4 citation statements)

References 18 publications

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“…Lung transplantation may be a promising treatment for end-stage respiratory failure following PCPF [ 9 , 10 ]. Since fibrotic disease affects around one-third of patients with a severe pulmonary form of COVID-19; this indication could represent a considerable number of patients in the near future [ 11 , 12 , 13 , 14 ].…”

Section: Resultsmentioning

confidence: 99%

New Aspects of Lung Transplantation: A Narrative Overview Covering Important Aspects of Perioperative Management

Fessler

Finet

Fischler

et al. 2022

Life

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The management of lung transplant patients has continued to evolve in recent years. The year 2021 was marked by the publication of the International Consensus Recommendations for Anesthetic and Intensive Care Management of Lung Transplantation. There have been major changes in lung transplant programs over the last few years. This review will summarize the knowledge in anesthesia management of lung transplantation with the most recent data. It will highlight the following aspects which concern anesthesiologists more specifically: (1) impact of COVID-19, (2) future of transplantation for cystic fibrosis patients, (3) hemostasis management, (4) extracorporeal membrane oxygenation management, (5) early prediction of primary graft dysfunction, and (6) pain management.

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Section: Resultsmentioning

confidence: 99%

New Aspects of Lung Transplantation: A Narrative Overview Covering Important Aspects of Perioperative Management

Fessler

Finet

Fischler

et al. 2022

Life

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“…Select patients with COVID-related acute respiratory distress syndrome (CARDS) requiring extracorporeal membrane oxygenation (ECMO) for an extended period with no potential for recovery, and post-COVID-19 pulmonary fibrosis are being considered for lung transplantation [44]. It is crucial to ensure that appropriate time is allowed for the lungs to recover before patients are considered for lung transplant, especially in patients with organizing pneumonia who have the potential to recover over time, although this recovery may take months [45].…”

Section: Lung Transplantationmentioning

confidence: 99%

Multidisciplinary Management Strategies for Long COVID: A Narrative Review

Prusinski,

Yan,

Klasova

et al. 2024

Cureus

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of infections to date and has led to a worldwide pandemic. Most patients had a complete recovery from the acute infection, however, a large number of the affected individuals experienced symptoms that persisted more than 3 months after diagnosis. These symptoms most commonly include fatigue, memory difficulties, brain fog, dyspnea, cough, and other less common ones such as headache, chest pain, paresthesias, mood changes, muscle pain, and weakness, skin rashes, and cardiac, endocrine, renal and hepatic manifestations. The treatment of this syndrome remains challenging. A multidisciplinary approach to address combinations of symptoms affecting multiple organ systems has been widely adopted. This narrative review aims to bridge the gap surrounding the broad treatment approaches by providing an overview of multidisciplinary management strategies for the most common long COVID conditions.

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“…Gogia et al presented a case of a 34-year-old male who developed end-stage pulmonary fibrosis following COVID-19 infection. A bilateral lung transplantation was carried out in this patient, and they were allowed a discharge from the hospital on day 15 following lung transplantation [ 53 ]. In accordance with Gogia et al, Hall et al also described a case of severe post-covid pulmonary fibrosis in a 52-year-old female.…”

Section: Lung Transplantation For Sars-cov-2 Infection—associated Ard...mentioning

confidence: 99%

How COVID-19 Affects Lung Transplantation: A Comprehensive Review

Vachtenheim

Novysedlák

Svorcova

et al. 2022

JCM

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Lung transplant (LuTx) recipients are at a higher risk of developing serious illnesses from COVID-19, and thus, we have closely reviewed the consequences of the COVID-19 pandemic on lung transplantation. In most transplant centers, the overall LuTx activity significantly declined and led to a specific period of restricting lung transplantation to urgent cases. Moreover, several transplant centers reported difficulties due to the shortage of ICU capacities. The fear of donor-derived transmission generated extensive screening programs. Nevertheless, reasonable concerns about the unnecessary losses of viable organs were also raised. The overall donor shortage resulted in increased waiting-list mortality, and COVID-19-associated ARDS became an indication of lung transplantation. The impact of specific immunosuppressive agents on the severity of COVID-19 varied. Corticosteroid discontinuation was not found to be beneficial for LuTx patients. Tacrolimus concentrations were reported to increase during the SARS-CoV-2 infection, and in combination with remdesivir, tacrolimus may clinically impact renal functions. Monoclonal antibodies were shown to reduce the risk of hospitalization in SOT recipients. However, understanding the pharmacological interactions between the anti-COVID-19 drugs and the immunosuppressive drugs requires further research.

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Lung transplantation for post‐COVID‐19 pulmonary fibrosis

Cited by 8 publications

References 18 publications

New Aspects of Lung Transplantation: A Narrative Overview Covering Important Aspects of Perioperative Management

New Aspects of Lung Transplantation: A Narrative Overview Covering Important Aspects of Perioperative Management

Multidisciplinary Management Strategies for Long COVID: A Narrative Review

How COVID-19 Affects Lung Transplantation: A Comprehensive Review

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