2024
DOI: 10.3390/ijms25168981
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Lupus Nephritis from Pathogenesis to New Therapies: An Update

Annalisa Roveta,
Emanuele Luigi Parodi,
Brigida Brezzi
et al.

Abstract: Lupus Nephritis (LN) still represents one of the most severe complications of Systemic Lupus Erythematosus (SLE) and a major risk factor for morbidity and mortality. However, over the last few years, several studies have paved the way for a deeper understanding of its pathogenetic mechanisms and more targeted treatments. This review aims to provide a comprehensive update on progress on several key aspects in this setting: pathogenetic mechanisms of LN, including new insight into the role of autoantibodies, com… Show more

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