Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in calcium oxalate nephrolithiasis: the underlying mechanisms

Gao, Xiaomin; Lin, Binwei; Chen, Chen; Fang, Ziyu; Yang, Jinzhao; Wu, Shuzhi; Chen, Qing; Zheng, Kewen; Yu, Zhixian; Li, Yeping; Gao, Xiaofeng; Lin, Guanyang; Chen, Lianguo

doi:10.1039/d4fo00042k

Food Funct.

2024

DOI: 10.1039/d4fo00042k

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Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in calcium oxalate nephrolithiasis: the underlying mechanisms

Xiaomin Gao,

Binwei Lin,

Chen Chen

et al.

Abstract: Several mechanisms underlying nephrolithiasis, one of the most common urological diseases, involve calcium oxalate formation, including oxidative stress, inflammatory reactions, fibrosis, pyroptosis, and apoptosis. Although lycopene has strong antioxidant activity,...

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Cited by 7 publications

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Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Tufail,

Bader Ul Ain,

Noreen

et al. 2024

Food Science & Nutrition

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Certain carotene components, such as lycopene and beta‐carotene, are found in tomatoes, carrots, sweet potatoes, etc. and are good for human health. It gives plants their distinctive red color. A class of lipid‐soluble natural pigments known as carotenoids is the precursor of vitamin A and is vital for antioxidant defense against peroxides in cells and tissues. This review provides an overview of the current state of knowledge and research on the sources, structures, physiochemical properties, absorption and metabolism, functional advantages, and prevention of many diseases associated with lycopene and beta‐carotene. These antioxidants have been linked to a lower risk of cardiovascular disease and cancer, and they also help draw pollinators to flowers. Carrots and sweet potatoes are also rich sources of beta‐carotene, which strengthens the immune system and improves eye health. The vivid color of many plants reproductive organs, including flowers and fruits, is caused by carotenoid, a secondary metabolite that is produced in plastids. The distinctive red color and many other health advantages are attributed to lycopene. When ingested through food or supplements, lycopene and beta‐carotene help manage and prevent a number of diseases, including cancer, metabolic, inflammatory, cardiovascular, hepatic, ophthalmic, skeletal, and infertility disorders. The main point is that toxicity is uncommon, and these carotenoids are generally accepted to be safe at different doses. Including these nutrients in your diet can improve your general health and provide illness prevention.

show abstract

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Tufail,

Bader Ul Ain,

Noreen

et al. 2024

Food Science & Nutrition

View full text Add to dashboard Cite

show abstract

Comprehensive analysis and validation of TP73 as a biomarker for calcium oxalate nephrolithiasis using machine learning and in vivo and in vitro experiments

Zhou,

Wang,

Cai

et al. 2024

Urolithiasis

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Characterization, Extraction, and Encapsulation Technologies of Lycopene and Applications in Functional Food Products: An Updated Review

Bakhshizadeh,

Moghaddam,

Tavassoli

et al. 2024

Food Bioprocess Technol

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Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in calcium oxalate nephrolithiasis: the underlying mechanisms

Abstract: Several mechanisms underlying nephrolithiasis, one of the most common urological diseases, involve calcium oxalate formation, including oxidative stress, inflammatory reactions, fibrosis, pyroptosis, and apoptosis. Although lycopene has strong antioxidant activity,...

Cited by 7 publications

References 49 publications

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Comprehensive analysis and validation of TP73 as a biomarker for calcium oxalate nephrolithiasis using machine learning and in vivo and in vitro experiments

Characterization, Extraction, and Encapsulation Technologies of Lycopene and Applications in Functional Food Products: An Updated Review

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