Lymph Node Biopsies: A Hospital Based Retrospective Study

Shrestha, A.; Chalise, Pawan Raj; Shrestha, Merina

doi:10.31729/jnma.342

Cited by 9 publications

(17 citation statements)

References 5 publications

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“…4,10 The mixed cellularity type is the most common pattern in the current study, in agreement with other studies. 17,19 In the present study, metastatic tumors was the fourth commonest cause of lymphadenopathy constituting 12.57% cases, which is similar to the study of Shrestha AK et al 16 In agreement with others, majority of the patients (62.5%) were above the age of 45 years. 4,16 Out of 24 metastatic lesions, adenocarcinoma and squamous cell carcinomas were common comprising 37.5% and 25% respectively.…”

Section: Discussionsupporting

confidence: 92%

“…In agreement with other studies benign lesions were more frequent comprising 70.2% of lymph node enlargement and malignant lesions constituted 29.8%. 15,16 In contrast, a study done by Olu-Eddo AN et al 10 revealed malignancy being the predominant lesion constituting 55% of cases. The higher incidence of malignant tumors are also documented in the western series.…”

Section: Discussionmentioning

confidence: 92%

“…This is consistent with virtually all other lymph node studies. 15,16 Next common group includes axillary and abdominal lymph node biopsies which comprised 14.7% and 14.13% respectively. The overall diagnostic yield of lymph node biopsy was 64.4%.…”

Section: Discussionmentioning

confidence: 99%

“…3,4 The studies performed in other developing countries also showed TB lymphadenitis being the most common cause of lymphadenopathy. 16,19,20 The high incidence of TB has been attributed to the low socio-economic status and the attendant poor standard of living in the third world countries. 21 In the western countries, infections like TB have become rare and malignancies including lymphoma are the predominant causes of lymph node enlargement.…”

Section: Discussionmentioning

confidence: 99%

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Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

Rahman¹,

Biswas²,

Siddika

et al. 2012

J Enam Med Col

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Background: Lymphadenopathy is a common manifestation of a large variety of disorders,both benign and malignant. It is essential to define the pattern of disorders presenting primarily as lymph node enlargement in a particular environment. Histopathological examination of the lymph node biopsies is a gold standard test in the distinction between reactive and malignant lymphoid proliferations as well as for detailed subtyping oflymphomas. We designed this study in our population for histopathological evaluation of lymph nodes that might be helpful for clinical management of these lesions. Objective: Histopathological evaluation of lymphadenopathy from excised specimen, in relation to ageand sex of the patients, and distribution of the lymph nodes. Materials and Methods: It was a retrospective cross sectional study conducted in the department of Pathology, Enam Medical College & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. Lymph node biopsies of all patients of both sexes and all age groups were included.Metastatic lymph nodes associated with evidence of primaries elsewhere in the body were excluded from the study. Total 191 lymph node biopsies were selected for histopathological evaluation. Among these 90 (47.12%) were from males and 101 (52.88%) were from females with male to female ratio being 1:2.1. The age of the patients ranged from 2 to 85 years with a mean age of 35.73 ± 18 years. Results: Cervical lymph nodes were the most common (56%) biopsied group. Of the 191 cases 59 cases (30.89%) were reactive lymphadenitis, 64 cases (33.5%) were tuberculosis, 2 cases (1.05%) were non-caseous granuloma, 11 cases (5.76%) were Hodgkin lymphoma, 22 cases (11.52%) were non-Hodgkin lymphoma, 24 cases (12.57%) were metastatic neoplasm and 9 cases (4.7%) were other lesions. Conclusion: Tuberculosis was the most common cause of lymphadenopathy, followed by reactive lymphadenitis and the cervical group of lymph nodes was most frequently affected

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

Rahman¹,

Biswas²,

Siddika

et al. 2012

J Enam Med Col

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“…1,2 Cervical lymphadenopathy is usually defined as cervical lymph nodal tissue measuring more than 1 cm in diameter. 3 This can be presented as isolated or as a part of generalized lymphadenopathy. Enlarged palpable cervical lymph node as a primary presenting sign is a very common problem in clinical practice.…”

mentioning

confidence: 99%

Histomorphological Pattern of Cervical Lymphadenopathy

Rahman¹,

Biswas²,

Siddika³

et al. 2013

J Enam Med Col

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Background: Enlarged palpable cervical lymph nodes as a primary presenting sign are very common and may be due to inflammatory lesions and tumors. Correlation between clinical findings and laboratory data is essential in arriving at a diagnosis. In patients presenting with cervical lymphadenopathy, excision biopsy provides material to establish an early diagnosis. We designed this study in our population for histological evaluation of cervical lymph node biopsies that might be important in the management of these patients. Objective: Histopathological evaluation of different diseases involving the cervical lymph nodes in relation to age and sex of the study population. Materials and Methods: It was a cross sectional study conducted in the department of Pathology, Enam Medical College & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. A total of 107 patients were evaluated for specific cause of cervical lymphadenopathy in relation to age and sex. Lymph node biopsies of all patients of both sexes and all age groups were included in the study. Results: Among the 107 subjects 58 (54.2%) were males and 49 (45.8%) were females with a male to female ratio of 1.2:1. The age of the patients ranged from 2 to 85 years with a mean age of 32.68 ± 18.01 years. Of the 107 lymph node biopsies, 34 cases (31.8%) were reactive lymphadenitis, 41 cases (38.3%) were tuberculosis, 2 cases (1.9%) were non-caseous granuloma, 6 cases (5.6%) were Hodgkin lymphoma, 8 cases (7.5%) were non-Hodgkin lymphoma, 12 cases (11.2%) were metastatic neoplasm and 4 cases (3.7%) were other specific lesions. Conclusion: The commonest cause of cervical lymphadenopathy was tuberculosis, followed by reactive lymphadenitis, lymphoma and metastatic neoplasm

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Granulomatous inflammation in lymph nodes of the head and neck—a retrospective analysis of causes in a population with very low incidence of tuberculosis

2020

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These are correct 2. The sentence that begins with "For the most common clinical diagnoses…" has been modified. Please check if the intended meaning is retained. Otherwise, please amend as necessary. ok 3. Please check if the section headings are assigned to appropriate levels."Settings" and "aim" were intended as subheadings/levels under the introduction 4. The sentence that begins with "The Danish island of Funen…" has been modified. Please check if the intended meaning is retained. Otherwise, please amend as necessary. ok Bold entries inTable 5 are italicized. Please specify the significance of emphasis in the form of a table footnote. Otherwise, please amend as necessary. Statistically significant results are italicized.6. If applicable, please provide the access dates of references # 7

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Lymph Node Biopsies: A Hospital Based Retrospective Study

Abstract: Abstract

Cited by 9 publications

References 5 publications

Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

Histomorphological Pattern of Cervical Lymphadenopathy

Granulomatous inflammation in lymph nodes of the head and neck—a retrospective analysis of causes in a population with very low incidence of tuberculosis

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