Lymph-node metastasis in squamous cell carcinoma of the lip

Califano, Luigi; Zupi, Aldo; Massari, P S; Giardino, C

doi:10.1016/s0901-5027(05)80053-0

Cited by 40 publications

(32 citation statements)

References 19 publications

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“…Califona ve ark. (22) Klinik N+ hastalara supraomohiyoid veya bölge 4 ve 5'i içeren genişletilmiş boyun diseksiyonu önermişlerdir (23,24) . Dudak kanserleri en sık olarak submandibüler ve submental lenf nodlarına metastaz yaptığından N0 hastalara yapılacak boyun diseksiyonu en azından supraomohyoid boyun disseksiyonu olması gerektiği konusunda görüşler artmaktadır (20) .…”

Section: Discussionunclassified

Our clinical approach to lip cancer; surgery and reconstruction principles

Koç¹,

Acıpayam²,

Koçak³

et al. 2017

Okmeydani Medical Journal

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Section: Discussionunclassified

Our clinical approach to lip cancer; surgery and reconstruction principles

Koç¹,

Acıpayam²,

Koçak³

et al. 2017

Okmeydani Medical Journal

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“…Lymph node metastases occur firstly in the neck in the submandibular and submental lymph nodes. For patients with lymph nodes on palpation, supraomohyoid or functional neck dissection is generally recommended [18]. However, all lymph nodes that can be clinically palpated may not be malignant.…”

Section: Discussionmentioning

confidence: 99%

Is neck dissection necessary in early stage lower lip carcinomas necessary?

Kahveci¹,

C²,

Demir³

et al. 2016

Med-Science

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Lower lip tumours are the most common of all oral cavity tumours. The purpose of this article was to analyse neck metastasis rates of early stage lower lip carcinomas and to evaluate possible correlations of histological parameters with neck metastasis. A retrospective review was made of 37 patients in respect of the dissection type, preoperative detection of lymphadenopathy by palpation or computed tomography (CT), tumour size and degree of histological differentiation. An experienced pathologist also re-evaluated the specimens and examined tumour depth and muscle invasion. Types of neck dissection were bilateral supraomohyoid in 20, unilateral supraomohyoid in 8, bilateral suprahyoid in 5 and unilateral suprahyoid in 1 patient. All the carcinomas were squamous cell carcinoma (SCC) and T stages were T1 in 32 and T2 in 5. Preoperatively, 4 patients had palpable lymph nodes and 9 patients had lymph nodes on CT scan, but none of these patients had histologically positive lymph node metastasis. Histological node metastasis was found in only 1 patient who had stage T1 tumour, no palpable or detected lymph node, no muscular invasion and very limited tumour depth. Tumour size, differentiation degree, tumour depth and muscle invasion do not seem to be sensitive indicators for the prediction of lymph node metastasis in early stage lower lip carcinomas. The necessity of neck dissection in early stage lower lip carcinomas should be reconsidered in a large series of patients.

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“…Whereas some researchers propose a 'wait and see' strategy (Califano et al, 1994;Zitsch et al, 1999), others recommend neck dissection in most cases (Altinyollar et al, 2002b;Bucur and Stefanescu, 2004;Kowalski et al, 1993;Medina and Byers, 1989). The former put patients with occult metastasis at risk of missing LNM which reduces their prognosis, the others can be claimed to perform unnecessary dissections and 'overtreatment' (Salgarelli et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, combining these factors into an easy to handle prediction model was not done in previous studies, and locoregional lymph node management (for example, indications for selective neck dissection in clinical N0 cases) is still controversial (Khalil et al, 2008;Moretti et al, 2011;Salgarelli et al, 2009;Vartanian et al, 2004;Vukadinovic et al, 2007). Some authors prefer to 'wait and see' and suggest neck dissection only in clinical Nþ cases (Califano et al, 1994;Zitsch et al, 1999), whereas others suggest more aggressive neck management with elective lymph node dissection in many cN0 patients (Altinyollar et al, 2002b;Bucur and Stefanescu, 2004;Kowalski et al, 1993;Medina and Byers, 1989).…”

Section: Introductionmentioning

confidence: 99%