Lymphogranuloma inguinale

Comparative Studies on the Pancreatic Islets

“…Also, in experimentally diabetic rats and guinea pigs there is a relative or even absolute increase in D-cells (Hellerstrom, 1963;Hellman and Petersson, 1963 ;Kobayashi et al, 1964), and these findings raise the question whether the enlarged number of D-cells in human diabetes mellitus indicates areaction to the diabetic disorders rather than a primary cause. Such a reaction could alleviate or compensate the effects of insulin deficiency in two ways: (1) by secretion of a"protective" hormone (e.g.…”