2007
DOI: 10.1016/j.ejso.2007.01.009
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Lymphvascular space involvement compromises the survival of patients with stage I endometrial cancer: Results of a multicenter study

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Cited by 54 publications
(43 citation statements)
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“…In a study by Gemer et al, LVSI was a predictor of FFS in FIGO stage 1 endometrial cancer patients. 19 The risk of death doubled when LVSI was present. LVSI in the present study was not further classified as mild, moderate or severe as described by Sykes et al 20 The authors noted the density of lymphatic invasion as represented by the number of lymphatic spaces occupied on the worst histological slide offered no further clinically useful information than mere presence or absence of LVSI.…”
Section: Lymph-vascular Space Invasionmentioning
confidence: 99%
“…In a study by Gemer et al, LVSI was a predictor of FFS in FIGO stage 1 endometrial cancer patients. 19 The risk of death doubled when LVSI was present. LVSI in the present study was not further classified as mild, moderate or severe as described by Sykes et al 20 The authors noted the density of lymphatic invasion as represented by the number of lymphatic spaces occupied on the worst histological slide offered no further clinically useful information than mere presence or absence of LVSI.…”
Section: Lymph-vascular Space Invasionmentioning
confidence: 99%
“…30,31 As such, the presence of LVSI in endometrial cancer is a well-known predictive factor for relapse and decreased DFS. 32,33 However, the potential risk of LVSI with IUM use during minimally invasive hysterectomy for endometrial cancer raises an important clinical question with controversial implications for endometrial cancer survival.…”
Section: Discussionmentioning
confidence: 99%
“…3,9,22,23 Whereas these studies all had central pathology review done, the current study included patients who had LVSI according to the primary pathologist. Interestingly, the findings of these studies are in line with our findings in the clinical practice setting.…”
Section: Discussionmentioning
confidence: 99%