Lyotropic liquid crystalline 2D and 3D mesophases: Advanced materials for multifunctional anticancer nanosystems

Araújo-Silva, Henrique; Teixeira, Patricia V.; Gomes, Andreia C.; Lúcio, Marlene; Lopes, Carla M.

doi:10.1016/j.bbcan.2023.189011

Cited by 1 publication

(2 citation statements)

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“…An overview of clinical applications has been given recently. [39] LNPs [38] have received public recognition in the development of mRNA-based vaccines against COVID-19 from BioN-Tech/Pfizer and Moderna. [27,38] These LNPs encapsulate mRNA encoding the sequence of the spike protein of SARS-CoV-2 and are delivered to the body by injection.…”

Section: Liquid Crystalline Nanoparticle Carriersmentioning

confidence: 99%

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Phospholipid Membranes as Chemically and Functionally Tunable Materials

Huster,

Maiti,

Herrmann

2024

Advanced Materials

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The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes. Its building blocks are phospholipids and cholesterol. Their amphiphilic structure spontaneously leads to the formation of a bilayer in aqueous environment. Lipids are not just structural elements. Individual lipid species, the lipid membrane structure, and lipid dynamics influence and regulate membrane protein function. An exciting field is emerging where the membrane‐associated material properties of different bilayer systems are used in designing innovative solutions for widespread applications across various fields, such as the food industry, cosmetics, nano‐ and biomedicine, drug storage and delivery, biotechnology, nano‐ and biosensors, and computing. Here, the authors summarize what is known about how lipids determine the properties and functions of biological membranes and how this has been or can be translated into innovative applications. Based on recent progress in the understanding of membrane structure, dynamics, and physical properties, a perspective is provided on how membrane‐controlled regulation of protein functions can extend current applications and even offer new applications.

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Section: Liquid Crystalline Nanoparticle Carriersmentioning

confidence: 99%

“…Due to the continuous and prolonged release of chemotherapeutic agents, the prerequisite for effective containment of tumor growth is satisfied in principle. [38,39]…”

Section: Liquid Crystalline Nanoparticle Carriersmentioning

confidence: 99%