Lysosomes: Biology, Diseases, and Therapeutics 2016 Help me understand this report
Lysosomal Membrane Permeabilization in Cell Death
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“…Hence, it is possible that phospholipases secreted by P. aeruginosa could disrupt the phagolysosomal membrane, allowing pseudolysin to leak out. Indeed it is not without precedence as phospholipase C is known to destabilize and permeabilize membranes [267,268].…”
Section: Explaining the Presence Of Pseudolysin In The Host Cytoplasmmentioning
confidence: 99%
“…Hence, it is possible that phospholipases secreted by P. aeruginosa could disrupt the phagolysosomal membrane, allowing pseudolysin to leak out. Indeed it is not without precedence as phospholipase C is known to destabilize and permeabilize membranes [267,268].…”
Section: Explaining the Presence Of Pseudolysin In The Host Cytoplasmmentioning
confidence: 99%
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