M Protein Gene Type Distribution among Group A Streptococcal Clinical Isolates Recovered in Mexico City, Mexico, from 1991 to 2000, and Durango, Mexico, from 1998 to 1999: Overlap with Type Distribution within the United States

Espinosa, Luz Elena; Li, Zhongya; Barreto, Demóstenes Gómez; Jaimes, E Calderón; Rodrı́guez, Romeo S; Sakota, Varja; Facklam, Richard R.; Beall, Bernard

doi:10.1128/jcm.41.1.373-378.2003

Cited by 49 publications

(23 citation statements)

References 13 publications

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“…In contrast, emm type 28, followed by types 12, 81, 4, and 89, was the leading type among noninvasive cases. Finally, emm type 12 was the most prevalent type among noninvasive throat isolates, which is in agreement with previous findings [35].…”

Section: Discussionsupporting

confidence: 82%

Molecular and Clinical Characteristics of Invasive Group A Streptococcal Infection in Sweden

Darenberg

Luca-Harari

Jasir

et al. 2007

Clinical Infectious Diseases

165

107

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Background. The incidence and severity of invasive group A streptococcal infection demonstrate great variability over time, which at least, in part, seems to be related to group A streptococcal type distribution among the human population.Methods. An enhanced surveillance study of invasive group A streptococcal infection (746 isolates) was performed in Sweden from April 2002 through December 2004. Noninvasive isolates from either the throat or skin (773 isolates) were collected in parallel for comparison. Clinical and epidemiological data were obtained from 88% of patients with invasive disease and were related to isolate characteristics, including T type, emm sequence type, and the presence of 9 superantigen genes, as well as pulsed-field gel electrophoresis pattern comparisons of selected isolates.Results. The annual incidence was 3.0 cases per 100,000 population. Among the patients with invasive disease, 11% developed streptococcal toxic shock syndrome, and 9.5% developed necrotizing fasciitis. The overall casefatality rate was 14.5%, and 39% of the patients with streptococcal toxic shock syndrome died ( ). The T3/ P ! .001 13/B3264 cluster accounted for 33% of invasive and 25% of noninvasive isolates. Among this most prevalent type cluster, emm types 89 and 81 dominated. Combined results from pulsed-field gel electrophoresis, emm typing, and superantigen gene profiling identified subgroups within specific emm types that are significantly more prone to cause invasive disease than were other isolates of the same type.Conclusions. This study revealed a changing epidemiology of invasive group A streptococcal infection in Sweden, with emergence of new emm types that were previously not described. The results also suggest that some clones may be particularly prone to cause invasive disease.

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Section: Discussionsupporting

confidence: 82%

Molecular and Clinical Characteristics of Invasive Group A Streptococcal Infection in Sweden

Darenberg

Luca-Harari

Jasir

et al. 2007

Clinical Infectious Diseases

165

107

View full text Add to dashboard Cite

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“…Our finding of emm12 to be common in throat isolates is in line with those previously reported [10,17,18]. Our finding of emm1 strains as a cause for pharyngitis is also commonly known, although emm1 is often considered to cause especially invasive disease [10,[17][18][19]. In our study material, emm77 was found especially in skin and wound swabs, but it was also the most common emm type in deep infection and blood isolates.…”

Section: Discussionsupporting

confidence: 93%

Distribution of emm types in invasive and non-invasive group A and G streptococci

Vähäkuopus

Vuento

Siljander

et al. 2011

Eur J Clin Microbiol Infect Dis

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Our study describes the emm type distributions of invasive and non-invasive group A streptococci (GAS) and group G streptococci (GGS) strains in one of the biggest Health Districts in Finland. A total of 571 GAS or GGS were recovered from patients with invasive or non-invasive infections during a 1-year period in 2008-2009 in Pirkanmaa Health District in Finland. We describe here the emm type distributions of GAS and GGS collected from throat (n = 246), pus (n = 217), deep tissue (n = 56) and blood (n = 52). The most common emm types among GAS were emm77, emm1, emm28, emm89 and emm12. Among GGS, the most common emm types were stG480, stG643, stG6, stC6979 and stG485. Some emm types were found to associate with certain infection focus. In GAS, emm77 associated with pus isolates, whereas emm1 and emm12 were more frequent among throat isolates. In GGS, stG480 was more commonly found from throat isolates.

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“…Our study shows that emm types identified among this population is vastly different from those reported other parts of the world (Hu et al 2002;Ho et al 2003;Gardiner et al 1998;Dicuonzo et al 2001;Espinosa et al 2003;Alberti et al 2003). Interestingly, it is also markedly different from those reported from other endemic regions such as Ethiopia (Tewodros and Kronvall 2005).…”

Section: Resultscontrasting

confidence: 75%

Prevalence of emm types of Group A streptococci recovered from school children and hospital patients in Bangalore City, India

Gowda

Melbin

Patil

et al. 2010

World J Microbiol Biotechnol

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A total of sixty non repetitive isolates of group A streptococci (GAS) recovered from throat cultures of asymptomatic school children (n = 36), school children with clinical pharyngitis (n = 9) and hospital patients with clinical pharyngitis (n = 4) as well as diverse clinical samples from invasive GAS disease (n = 11) were subjected to emm typing. A total of 35 emm types including 3 new subtypes were identified among them. Types emm 12 (16.6%) and emm 71 (6.6%) were the most prevalent. The distribution of emm types identified among school children were similar to those encountered among invasive isolates but was significantly different from those reported elsewhere in India. Our study confirms the high diversity among Indian GAS isolates as well as significant regional differences among the distribution of emm types.

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M Protein Gene Type Distribution among Group A Streptococcal Clinical Isolates Recovered in Mexico City, Mexico, from 1991 to 2000, and Durango, Mexico, from 1998 to 1999: Overlap with Type Distribution within the United States

Cited by 49 publications

References 13 publications

Molecular and Clinical Characteristics of Invasive Group A Streptococcal Infection in Sweden

Molecular and Clinical Characteristics of Invasive Group A Streptococcal Infection in Sweden

Distribution of emm types in invasive and non-invasive group A and G streptococci

Prevalence of emm types of Group A streptococci recovered from school children and hospital patients in Bangalore City, India

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