M1/M2 macrophages: origin, phenotype, methods of production, interaction with natural killer cells and trophoblast
A. S. Zhguleva,
M. S. Zementova,
S. A. Selkov
et al.
Abstract:This review presents current data on the origin of monocytes/macrophages, the conditions necessary for the differentiation of monocytes into M1 or M2 macrophages. Three subpopulations of peripheral blood monocytes are described: (I) classical – the main subpopulation (85-90%), effectively carrying out phagocytosis; (II) intermediate monocytes (5-10%) – participate in antigen processing and presentation, in angiogenesis, vascular endothelium restoration; (III) non-classical monocytes (10%) - "patrol" vascular n… Show more
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