2016
DOI: 10.1038/nature20577
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m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

Abstract: (2016) m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination. Nature, 540 (7632). pp. 301-304. ISSN 1476-4687 Access from the University of Nottingham repository: http://eprints.nottingham.ac.uk/39448/1/Nature_m6A_2016.pdf Copyright and reuse:The Nottingham ePrints service makes this work by researchers of the University of Nottingham available open access under the following conditions. This article is made available under the University of Nottingham End User licence … Show more

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Cited by 534 publications
(601 citation statements)
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“…Drosophila melanogaster Vir is required for promoting certain alternative splicing events associated with female gametogenesis and X chromosome dosage compensation (Hilfiker et al ., 1995; Ortega et al ., 2003; Haussmann et al ., 2016; Lence et al ., 2016). We isolated poly(A) + RNA from vir‐1 root tips and carried out Illumina RNA sequencing.…”
Section: Resultsmentioning
confidence: 99%
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“…Drosophila melanogaster Vir is required for promoting certain alternative splicing events associated with female gametogenesis and X chromosome dosage compensation (Hilfiker et al ., 1995; Ortega et al ., 2003; Haussmann et al ., 2016; Lence et al ., 2016). We isolated poly(A) + RNA from vir‐1 root tips and carried out Illumina RNA sequencing.…”
Section: Resultsmentioning
confidence: 99%
“…A regulatory role of N 6‐adenosine methylation (m 6 A) in development and in determining cell fate has been demonstrated in major model systems such as mouse, Drosophila melanogaster and Saccharomyces cerevisiae (Clancy et al ., 2002; Hongay & Orr‐Weaver, 2011; Geula et al ., 2015; Haussmann et al ., 2016). m 6 A has recently been shown to have a crucial role during murine stem cell development, where it prompts stem cell differentiation from their naïve stage (Geula et al ., 2015).…”
Section: Discussionmentioning
confidence: 99%
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