Machine Learning and Clinical Informatics for Improving HIV Care Continuum Outcomes

Ridgway, Jessica P; Lee, Alice; Devlin, Samantha; Kerman, Jared; Mayampurath, Anoop

doi:10.1007/s11904-021-00552-3

Cited by 22 publications

(11 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The impacts of early COVID-19 disruptions on ART adherence also varied across studies. It was widely expected that COVID-19 would interrupt access to ART with adverse effects on adherence, particularly given ubiquitous disruptions to accessing care, pharmacies, and the impacts on factors known to influence adherence, such as stress and substance use [72]. Globally, an estimated one in five PLWH were unable to access their HIV care provider, and close to half of PLWH were unable to access ART refills remotely, with the least access occurring in Belarus, Brazil, Kazakhstan, Mexico, and Russia [73].…”

Section: Access To Health Servicesmentioning

confidence: 99%

Social and Behavioral Impacts of COVID-19 on People Living with HIV: Review of the First Year of Research

Kalichman

El-Krab

2021

Curr HIV/AIDS Rep

View full text Add to dashboard Cite

Purpose of the ReviewThe SARS-CoV-2 (COVID-19) pandemic brought unprecedented social change with the most severe impacts on the most vulnerable populations, including people living with HIV (PLWH). This review examined findings from empirical studies of social and behavioral impacts of COVID-19 on PLWH in the first year of the pandemic. Recent Findings Impacts of COVID-19 on PLWH fit within an HIV syndemics framework, with overlapping COVID-19 and HIV comorbid conditions concerning mental health and structural inequality. Early impacts of COVID-19 on social isolation, emotional distress, stigma, and substance use varied across studies with few consistent patterns. Structural inequalities, particularly impacts on food security and housing stability, were observed more consistently and globally. Summary COVID-19 intersects with HIV infection along with multiple interlocking comorbidities that are best characterized and understood within a syndemics framework. Keywords HIV-COVID-19 co-infection • Social impacts • Behavioral impacts • People living with HIV This article is part of the Topical Collection on Co-infections and Comorbidity * Seth C. Kalichman

show abstract

Section: Access To Health Servicesmentioning

confidence: 99%

Social and Behavioral Impacts of COVID-19 on People Living with HIV: Review of the First Year of Research

Kalichman

El-Krab

2021

Curr HIV/AIDS Rep

View full text Add to dashboard Cite

show abstract

“…Furthermore, clinical informatics and machine learning models have the potential to improve HIV care continuum outcomes. Clinical decision support systems and electronic warnings based on electronic medical records have been used effectively to improve HIV care continuum outcomes [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Progress of the Gulf Cooperation Council (GCC) Countries Towards Achieving the 95-95-95 UNAIDS Targets: A Review

Awaidy

Ghazy

Mahomed

2023

J Epidemiol Glob Health

View full text Add to dashboard Cite

Background In 2014, the Joint United Nations Programme on HIV/AIDS (UNAIDS) and partners launched the 90-90-90 targets. These were further updated to correspond to 95-95-95 by the year 2025. We present an overview of the progress made by Gulf Cooperated Council (GCC) countries towards meeting the global targets. Methods We extracted data from Global AIDS Monitoring (GAM), UNAIDS AIDS Info, HIV case reporting database, and the WHO global policy uptake for six countries: Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and the United Arab of Emirates (UAE) to assess the HIV/AIDS burden in the six GCC countries, and the progress towards achieving the 95-95-95 goal. Results By the end of 2021, an estimated 42,015 people living with HIV (PLHIV) were residing in the GCC countries with prevalence levels below 0.01%. Data from four GCC countries, Bahrain, Oman, Qatar and UAE, indicated that by 2021, 94%, 80%, 66%, and 85% of HIV-positive population knew their status, respectively. 68%, 93% (2020 data), 65%, 58% and 85% of PLHIV in Bahrain, Kuwait, Oman, Qatar and UAE who knew their status were on anti-retroviral therapy (ART), respectively, and 55%, 92%, 58% and 90% (2020 data) among those who were on ART had viral suppression in Bahrain, Kuwait, Oman and KSA, respectively. Conclusion The GCC countries have made great strides toward fulfilling the 95-95-95 targets, but the interim 2025 overall UNAIDS targets remain unmet. The GCC countries must strive diligently to accomplish the targets by emphasising early identification of the cases by enhanced screening and testing, as well as prompt commencement of ART therapy with viral load suppression.

show abstract

“…The same alert (potentially with a repaired antibody criterion) could be used to facilitate additional quality improvement interventions for hospitalised PWH. Indeed, there is a growing body of evidence that EMR data can be used to improve diagnosis, linkage and engagement in care for PWH 12–15. This analysis adds to that literature by determining sensitivity and PPV of an EMR alert and its individual elements.…”

Section: Discussionmentioning

confidence: 99%

Designing an electronic medical record alert to identify hospitalised patients with HIV: successes and challenges

El-Nahal

Grader‐Beck

Gebo

et al. 2022

BMJ Health Care Inform

View full text Add to dashboard Cite

ObjectivesElectronic medical record (EMR) tools can identify specific populations among hospitalised patients, allowing targeted interventions to improve care quality and safety. We created an EMR alert using readily available data elements to identify hospitalised people with HIV (PWH) to facilitate a quality improvement study intended to address two quality/safety concerns (connecting hospitalised PWH to outpatient HIV care and reducing medication errors). Here, we describe the design and implementation of the alert and analyse its accuracy of identifying PWH.MethodsThe EMR alert was designed to trigger for at least one of four criteria: (1) an HIV ICD-10-CM code in a problem list, (2) HIV antiretroviral medication(s) on medication lists, (3) an HIV-1 RNA assay ordered or (4) a positive HIV-antibody result. We used manual chart reviews and an EMR database search to determine the sensitivity and positive predictive value (PPV) of the overall alert and its individual criteria.ResultsOver a 24-month period, the alert functioned as intended, notifying an intervention team and a data abstraction team about admissions of PWH. Manual review of 1634 hospitalisations identified 18 PWH hospitalisations, all captured by the alert (sensitivity 100%, 95% CI 82.4% to 100.0%). Over the 24 months, the alert triggered for 1191 hospitalisations. Of these, 1004 were PWH hospitalisations, PPV=84.3% (95% CI 82.2% to 86.4%). Using fewer criteria (eg, using only ICD-10-CM codes) identified fewer PWH but increased PPV.ConclusionAn EMR alert effectively identified hospitalised PWH for a quality improvement intervention. Similar alerts might be adapted as tools to facilitate interventions for other chronic diseases.

show abstract

Machine Learning and Clinical Informatics for Improving HIV Care Continuum Outcomes

Cited by 22 publications

References 53 publications

Social and Behavioral Impacts of COVID-19 on People Living with HIV: Review of the First Year of Research

Social and Behavioral Impacts of COVID-19 on People Living with HIV: Review of the First Year of Research

Progress of the Gulf Cooperation Council (GCC) Countries Towards Achieving the 95-95-95 UNAIDS Targets: A Review

Designing an electronic medical record alert to identify hospitalised patients with HIV: successes and challenges

Contact Info

Product

Resources

About