Machine learning for acute kidney injury: Changing the traditional disease prediction mode

Abstract

Acute kidney injury (AKI) is a serious clinical comorbidity with clear short-term and long-term prognostic implications for inpatients. The diversity of risk factors for AKI has been recognized in previous studies, and a series of predictive models have been developed using traditional statistical methods in conjunction with its preventability, but they have failed to meet the expectations in limited clinical applications, the rapid spread of electronic health records and artificial intelligence machine learning technology has brought new hope for the construction of AKI prediction models. In this article, we systematically review the definition and classification of machine learning methods, modeling ideas and evaluation methods, and the characteristics and current status of modeling studies. According to the modeling objectives, we subdivided them into critical care medical setting models, all medical environment models, special surgery models, special disease models, and special nephrotoxin exposure models. As the first review article to comprehensively summarize and analyze machine learning prediction models for AKI, we aim to objectively describe the advantages and disadvantages of machine learning approaches to modeling, and help other researchers more quickly and intuitively understand the current status of modeling research, inspire ideas and learn from experience, so as to guide and stimulate more research and more in-depth exploration in the future, which will ultimately provide greater help to improve the overall status of AKI diagnosis and treatment.

Machine Learning Models for Point-of-Care Diagnostics of Acute Kidney Injury

“…To date, the application of machine learning in the care of AKI has mainly focused on the prediction of AKI. Thus, such AKI prediction models with short time windows could be compared with our AKI diagnosing models as references [19]. In an AKI prediction model for all-care setting conducted by Cronin et Although we compare the present AKI diagnosis model to AKI prediction models, the difference between these two models does exist.…”

Assessment of Risk Factors for Acute Kidney Injury with Machine Learning Tools in Children Undergoing Hematopoietic Stem Cell Transplantation

“…Artificial intelligence (AI) tools have already been used to assess the risk factors for AKI development in specific groups of patients, including those after cardiosurgery or on intensive care units [12][13][14]. AI implementation in the analysis of pediatric AKI has been highly successful in the neonatal population, but has not covered the issue of post-HSCT AKI sufficiently [15].…”

Predicting lung cancer's metastats' locations using bioclinical model

“…In this work, we propose a bio-physical model to predict from PET-CT imagery the locations of small-size metastasis that the current PET-CT methods are missing. Data-driven models are increasingly being utilized in the field of oncology ( 23 , 24 ). By utilizing patient-specific biological and clinical data, these models aim to provide a more comprehensive representation of the disease and its progression, thereby enabling more targeted and effective treatment strategies ( 25 , 26 ).…”