2017
DOI: 10.1016/j.inffus.2016.11.005
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Machine learning techniques to discover genes with potential prognosis role in Alzheimer’s disease using different biological sources

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Cited by 29 publications
(25 citation statements)
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“…Table 4 shows some studies in Alzheimer's disease and other forms of dementia via machine learning algorithms. The applications include diagnosis of Alzheimer's disease [115,116], diagnosis of dementias [117], and detection of Alzheimer's disease related regions [118], prediction of mild cognitive impairment patients for conversion to Alzheimer's disease [119,120], detection of dissociable multivariate morphological patterns [121], diagnosis of both Alzheimer's disease and mild cognitive impairment [122] and identification of genes related to Alzheimer's disease [125,126]. Alzheimer's disease: sensitivity = 85%, specificity = 82%, accuracy = 85%; Mild cognitive impairment: sensitivity = 84%, specificity = 81%, accuracy = 85% [125] Identification of genes related to Alzheimer's disease DT; QAR 33 90 genes are related to Alzheimer's disease [126] Identification of genes related to Alzheimer's disease ELM; RF; SVM 31 Sensitivity= 78.77%; Specificity= 83.1%; Accuracy = 74.67% DCNN = deep convolutional neural network; DT = decision tree; ELM = extreme learning machine; EM = expectation maximization; GA = genetic algorithm; LC = lasso classification; LDS = low density separation; LR = logistic regression; NBC = Naive Bayes classifier; QAR = quantitative association rules; RF = random forest; RLO = random linear oracle; RS = random subspace; SVM = support vector machine.…”
Section: Alzheimer's Disease and Other Forms Of Dementiamentioning
confidence: 99%
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“…Table 4 shows some studies in Alzheimer's disease and other forms of dementia via machine learning algorithms. The applications include diagnosis of Alzheimer's disease [115,116], diagnosis of dementias [117], and detection of Alzheimer's disease related regions [118], prediction of mild cognitive impairment patients for conversion to Alzheimer's disease [119,120], detection of dissociable multivariate morphological patterns [121], diagnosis of both Alzheimer's disease and mild cognitive impairment [122] and identification of genes related to Alzheimer's disease [125,126]. Alzheimer's disease: sensitivity = 85%, specificity = 82%, accuracy = 85%; Mild cognitive impairment: sensitivity = 84%, specificity = 81%, accuracy = 85% [125] Identification of genes related to Alzheimer's disease DT; QAR 33 90 genes are related to Alzheimer's disease [126] Identification of genes related to Alzheimer's disease ELM; RF; SVM 31 Sensitivity= 78.77%; Specificity= 83.1%; Accuracy = 74.67% DCNN = deep convolutional neural network; DT = decision tree; ELM = extreme learning machine; EM = expectation maximization; GA = genetic algorithm; LC = lasso classification; LDS = low density separation; LR = logistic regression; NBC = Naive Bayes classifier; QAR = quantitative association rules; RF = random forest; RLO = random linear oracle; RS = random subspace; SVM = support vector machine.…”
Section: Alzheimer's Disease and Other Forms Of Dementiamentioning
confidence: 99%
“…Fourteen different algorithms were employed in [115][116][117][118][119][120][121][122][123][124][125][126]. The datasets of Alzheimer's disease and other forms of dementia have relatively small sample size.…”
Section: Alzheimer's Disease and Other Forms Of Dementiamentioning
confidence: 99%
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“…Muitas pesquisas utilizam estruturas de Rede para realizar o pós-processamento das Regras de Associação a fim de facilitar a extração do conhecimento por intermédio da análise das relações extraídas dos dados (CHERN-TONG; AZIZ, 2018;MARTÍNEZ-BALLESTEROS et al, 2017;LI et al, 2017;MINELGA et al, 2017;MEI;PAPER et al, 2015;SELMANE;BOUSSAID;BENTAYEB, 2015). Apenas os trabalhos de Pandey et al (2009) e Chawla, Davis e Pandey (2004) apresentam abordagens que possuem um atributo alvo (item objetivo), mas sem nenhum tipo de garantia de que as relações observadas geram hipóteses verdadeiras ou que o conhecimento formulado possa ser utilizado em aplicações de diversas áreas.…”
Section: Lista De Ilustraçõesunclassified