Macro and Micro-Vascular Complications and their Risk Factors in Diabetes Mellitus Patients of Southern Punjab, Pakistan

Gillani, Ali Hassan; Bashir, Samra; Ahmed, Abu Bakar; Usman, Muhammad; Mustafa, Asim; Iqbal, Taha; Batool, Narjis

doi:10.5530/jppcm.2018.2.17

Cited by 3 publications

(5 citation statements)

References 20 publications

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“…Moreover, age and diastolic blood pressure were significantly associated with CAD and CVD. A study from Pakistan 13 reported the strong association between age and CAD that is consistent with the findings of present study. Serum triglycerides was a common significantly associated factor of CAD and PVD in this study, a finding consistent with published studies.…”

Section: Discussionsupporting

confidence: 92%

“…The rising trends in the prevalence of the complications was observed as compared to the previous studies. A study conducted in Punjab, Pakistan by Gillani et al 13 reported the prevalence of macro vascular complication in their study was 21.7%. While a study by Al-Khawlani et al 14 reported that 25.4% of their participants with DMT2 were having macro vascular complication.…”

Section: Discussionmentioning

confidence: 91%

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Macrovascular Complications and their risk factors in Type 2 Diabetic Patients in Hyderabad, Pakistan.

Munazza Shaikh,

Sadiq Ali Khowaja,

Allah Bachayo Rajar

et al. 2021

j Muhammad Med Coll

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Introduction: Diabetes mellitus (DM), is the universally occurring non-communicable disease as well as exemplary health problem affecting peo-ple worldwide.1 The number of cases of DM are rising at an enormous pace irrespective of any age, gender, economic status or ethnicity around the globe.Objective: To evaluate the macro-vascular complications and its correlation with different risk factors among type-2 diabetic patients.Methodology: This cross-sectional study was conducted at Red Crescent General Hospital Latifabad Hyderabad from October 2018 to October 2020. Type 2 diabetics of either gender, between age 20 and 70 years, on diabetic medication visited during the study duration were included in the study. Data related to socio-demographic details and clinical features was collect-ed from the participants using a written questionnaire. Collected data was analyzed using SPSS ver. 22.Results: Significant association (p<0.05) was demonstrated between Coro-nary artery diseases and the risk factors like; age of patient, the duration of diabetes mellitus, diastolic as well as systolic blood pressures, body mass index and serum triglycerides levels. While the statistically significant asso-ciation (p<0.05) of peripheral vascular diseases with the duration of diabe-tes mellitus, systolic blood pressure and serum triglyceride levels. Whereas, cerebrovascular disease was associated (p<0.05) with age, systolic and diastolic BP.Conclusion: The coronary artery disease seems to be most frequent macro-vascular complication among the type 2 diabetic patients. Whereas the risk factors including; advancing age, duration of diabetes mellitus, hyperten-sion, BMI as well as serum triglycerides levels are the most significant fac-tors for these complications.Key Words: Coronary artery disease, Cerebrovascular Disease, Diabetes Mellitus Type 2, Peripheral vascular disease

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 91%

Macrovascular Complications and their risk factors in Type 2 Diabetic Patients in Hyderabad, Pakistan.

Munazza Shaikh,

Sadiq Ali Khowaja,

Allah Bachayo Rajar

et al. 2021

j Muhammad Med Coll

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“…A Pakistani study by Gillani et al reported the strong association between age and CAD, which is consistent with the findings of present study. 16 Serum triglycerides was a common significantly associated (p<0.05) factor of CAD and PVD in this study. This may be due to fact that high serum triglycerides may lead to increase chances of thrombus formation within the vessels and lead to blockage of blood circulation in the vessels.…”

Section: Discussionsupporting

confidence: 53%

“…In comparison to previous studies, rising trends in the prevalence of complications were observed. A study conducted in Punjab, Pakistan by Gillani et al 16 reported the prevalence of macro vascular complication in their study was 21.7%. While a study by Li J. et al reported that comparable proportion of their participants with DMT2 were having macro vascular complication.…”

Section: Discussionmentioning

confidence: 91%

Vascular Complications and their Risk Factors in Patients of Diabetes Mellitus, Type 2

Farhad

Burghri²,

Memon

et al. 2023

J Islamabad Med Dental Coll

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Introduction: To evaluate the vascular complications and their correlation with different risk factors among type-2 diabetic patients in Hyderabad, Sindh, Pakistan. Methodology: Cross-sectional study was conducted at the department of medicine Isra University Hospital, Hyderabad from March to September 2021. Type 2 diabetics of either sex, between ages 20 and 70 years, on diabetic medication, were included in the study. While patients with type I diabetes, unconscious or with any mental health issues were excluded. A Non-random consecutive sampling technique was applied for the selection of participants. Socio-demographic, disease and medication information was collected using a written questionnaire while serum glucose level, albumin and lipid profile was analyzed. Results: Over half of the participants (51.72%) were females, while most (70.87%) of the participants were aged < 40 years. A total of 124(28.5%) patients showed symptoms of macro-vascular complications with most (16.78%) of them having coronary artery disease. A significant relation (p<0.05) was found between coronary artery disease and age, duration of diabetes, blood pressure, body mass index and serum triglycerides. Peripheral vascular disease was significantly related (p<0.05) to the duration of diabetes, systolic blood pressure and serum triglyceride. While significant relation (p<0.05) between cerebrovascular disease with age, systolic and diastolic BP was there. Conclusion: Coronary artery disease seems to be the most common macro-vascular complication among type 2 diabetic patients, with a high prevalence of risk factors such as advanced age, duration of DM, male sex, hypertension, Body Mass Index, and serum triglycerides. Keywords: Coronary artery disease, diabetes mellitus type 2, Macro-vascular complications, peripheral vascular disease.

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“…Over the last decade, some studies were conducted to evaluate the occurrence and risk factors of DM in rural and urban Pakistan [ 10 , 11 ] and others have evaluated co-morbidities associated with diabetes [ 12 , 13 ]. However, no study has estimated the KAP regarding DM, along with its treatment and management and risk factors in the general population of Punjab.…”

Section: Introductionmentioning

confidence: 99%

Knowledge, Attitudes and Practices Regarding Diabetes in the General Population: A Cross-Sectional Study from Pakistan

Gillani

Islam

Hayat

et al. 2018

IJERPH

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Background: Low knowledge about diabetes risk factors coupled with high disease prevalence is common in low-resource countries. This study evaluated diabetes-related knowledge, attitudes, and practices in the general population in Punjab (Pakistan). Methods: A cross-sectional study was conducted in five districts in Punjab from January to March 2017. Data were collected from 2019 adults aged 18–90 years through face-to-face interviews using a semi-structured questionnaire. The total knowledge score ranged from 0–9; a score ≥6 was considered adequate diabetes awareness. Descriptive statistics, chi-square tests, and linear and binary logistic regression were used for the analyses. Results: Respondents’ mean age was 32.92 ± 11.4 years. In total, 85.9% of respondents had heard of diabetes, and 30.1% knew about the glucose tolerance test. We found 2.3% of respondents scored zero for diabetes knowledge, 11.3% scored 9, and 47.4% scored ≥6 (adequate awareness). Being female (β = 0.37, 95% confidence interval [CI]: 0.16, 0.05; p = 0.001), socioeconomic status (β = 0.24, 95% CI: 0.12, 0.36; p < 0.001), being diabetic (β = 0.82, 95% CI: 0.53, 1.10; p < 0.001), and higher education (β = 0.25, 95% CI: 0.17, 0.33; p < 0.001) were significantly associated with knowledge score. Respondents with high socioeconomic status showed significantly higher positive attitudes compared with those with low socioeconomic status (adjusted odds ratio 1.57, 95% CI: 1.12, 2.24). Only 8.7% (30/343) of those diagnosed with diabetes had never undergone blood glucose screening since diagnosis. Conclusions: Knowledge of diabetes risk factors, management, and care is low in Pakistan’s general population. Targeted public education programs should be instigated at a national level to increase understanding of diabetes prevention and treatment.

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Macro and Micro-Vascular Complications and their Risk Factors in Diabetes Mellitus Patients of Southern Punjab, Pakistan

Cited by 3 publications

References 20 publications

Macrovascular Complications and their risk factors in Type 2 Diabetic Patients in Hyderabad, Pakistan.

Macrovascular Complications and their risk factors in Type 2 Diabetic Patients in Hyderabad, Pakistan.

Vascular Complications and their Risk Factors in Patients of Diabetes Mellitus, Type 2

Knowledge, Attitudes and Practices Regarding Diabetes in the General Population: A Cross-Sectional Study from Pakistan

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