Macrocarpals H, I, and J from the Leaves of Eucalyptus globulus

Abstract

A 50% EtOH extract of Eucalyptus globulus leaves yielded eight phloroglucinol--sesquiterpene-coupled constituents, including three novel compounds named macrocarpals, H, I, and J. Some of these compounds possessed antibacterial activity against oral pathogenic microorganisms with MIC values ranging from 0.20 micrograms/mL to 6.25 micrograms/mL. Inhibition of glucosyltransferase activity by these compounds was also noted.

Bioactive monoterpene glycosides conjugated with gallic acid from the leaves of Eucalyptus globulus

“…It is interesting that plants of the genus Eucalyptus have been shown to produce a number of unique structure types, gallic acid-monoterpene (Ito et al, 2000), phrologlucinolsesquiterpene and monoterpene (Osawa and Yasuda, 1996) coupled compounds (see Fig. 1).…”

Marker Constituents of the Natural Antioxidant Eucalyptus Leaf Extract for the Evaluation of Food Additives

“…[4][5][6] In addition to the antioxidants, the chemical constituents of the leaves have been investigated extensively to reveal the presence of a wide array of compounds, including monoterpenes, such as 1,8-cineole, sesquiterpenephloroglucinol derivatives, flavonoids, tannins, and related polyphenols. 3,[7][8][9][10][11][12][13] As part of studies evaluating official food additives conducted by research groups of the Ministry of Health, Labour and Welfare of Japan since 2003, eucalyptus leaf extract was found to include gallic acid, quercetin 3-O--D-glucuronide, kaempferol 3-O--D-glucuronide, globuluside, cryptmeridiol, 4-epi-cryptmeridiol, 3,13-dihydroxyurs-11-en-28-oic acid, -eudesmol, and macrocarpal I, of which the first three were the main constituents.…”

Preparative Isolation of Novel Antimicrobial Compounds from Pergidae sp. by Reversed-Phase High-Performance Liquid Chromatography

“…15.1 g (wet weight) larvae of the Australian sawfly sp. indet (Hymenoptera:Symphyta) was collected from eucalyptus trees on the Atherton Tablelands, Queensland, Australia and frozen in a dry-shipper containing liquid nitrogen.…”