Macular ultrastructural features in amblyopia using high-definition optical coherence tomography

Abstract

Using enhanced high-definition SD-OCT, amblyopic eyes demonstrated qualitative and quantitative differences in macular features, possibly representing signs of immaturity compared with normal fellow eyes.

Association Between Photoreceptor Regeneration and Visual Acuity Following Surgery for Rhegmatogenous Retinal Detachment

“…Perhaps the number of patients we included was insufficient to evaluate the aforementioned factors. Recent OCT studies have demonstrated the presence or absence of a foveal bulge at the central fovea is significantly associated with VA in eyes with albinism, 23 occult macular dystrophy, 24 amblyopia, 25 branch retinal vein occlusion, 26 and RRD. 27 Centripetal migration of cone cells and thinning of individual foveal cone OS reportedly results in an increase in foveal cone OS density.…”

“…Recent OCT studies have shown that the presence or absence of a foveal bulge at the central fovea is significantly correlated with VA in eyes with albinism, 23 occult macular dystrophy, 24 amblyopia, 25 and branch retinal vein occlusion. 26 Hasegawa et al 27 reported a significant correlation between the presence of foveal bulge and BCVA after successful RRD repair with vitrectomy.…”

Macular structural characteristics in children with Down syndrome

“…A value of 10 μm was chosen, as coefficients of repeatability for macular thickness measured by fdOCT in eyes with healthy retinas have been reported at 1.0 to 3.5 %, or up to about 9.5 μm [31,32]. Interocular differences in macular thickness of 0.0±13.4 μm as measured by fdOCT have been reported for children 6-17 years of age [21]. Using this standard deviation, we determined that a sample size of 16 in each group was sufficient.…”

“…Eye growth during childhood is a visually guided process, and degradation or alteration of visual input may disrupt growth [18]. Numerous studies have evaluated the effects of early abnormal visual experience in relation to macular thickness in children with strabismic and anisometropic amblyopia [19][20][21][22][23][24]. Despite the obvious ocular problems, in light of the unique challenges of retinal imaging in children, there are few reports on retinal structure in children with Down syndrome.…”

Macular Measurements Using Spectral-Domain Optical Coherence Tomography in Chinese Myopic Children

“…The advantages of SD-OCT include highly increased image acquisition, approximately twice the axial resolution, relatively reduced motion artifact, and significantly increased signal-tonoise ratio as compared with TD-OCT. 8,[10][11][12][13][14][15] Accordingly, several studies on macular thickness and volume using SD-OCT have been reported recently among children, young adults, or a wide range of age with one or mixed ethnicity. 9,14,[16][17][18][19][20][21][22] However, investigation of macular thickness and its relationship with refractive error or AL in Chinese myopic children using SD-OCT have yet to be reported.…”