Magnesium Sulfate in combination with Nifedipine in the treatment of Pregnancy-Induced Hypertension

Xiang, Cuiping; Zhou, Xuegui; Zheng, Xuelian

doi:10.12669/pjms.36.1.706

Cited by 3 publications

(3 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Magnesium sulfate has the antagonistic effect of Ca 2+ and is mainly used for anticonvulsion. It can reduce blood pressure by causing vascular dilation, further improve human microcirculation, and can be used for the treatment of hypertensive crisis [ 19 , 20 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH

Zhao²,

Gao³

et al. 2021

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Background. To observe the clinical effect of Pinggan Yiqi Yangshen recipe combined with labetalol hydrochloride and magnesium sulfate in the treatment of pregnancy-induced hypertension (PIH). Methods. A total of 126 patients with PIH diagnosed in our hospital from January 2016 to May 2018 were randomly divided into the control group and the experimental group, with 63 cases in each group. The control group was treated with labetalol combined with magnesium sulfate. On the basis of the control group, the experimental group was treated with Pinggan Yiqi Yangshen recipe. Clinical efficacy, blood pressure, renal function, and biochemical indexes were compared between the two groups. Moreover, pregnancy outcomes and adverse reactions were compared between the two groups. Results. After treatment, the total effective rate in the experimental group was higher than in the control group. Blood pressure and mean arterial pressure in the experimental group were more significantly downregulated than the control group. Renal function indexes and biochemical indexes in the experimental group were more significant than those in the control group. The incidence of cesarean section, preterm birth, and abnormal fetal heart rate in the experimental group was significantly lower than that in the control group. There was no difference in the incidence of fetal distress, postpartum hemorrhage, neonatal asphyxia, and adverse reactions between the two groups. Conclusion. Pinggan Yiqi Yangshen recipe combined with labetalol hydrochloride and magnesium sulfate can effectively reduce the blood pressure of patients with PIH, help patients to return to normal levels of biochemical indexes and renal function indexes, and improve pregnancy outcomes with high safety, which is worthy of further promotion and application in clinical practice.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH

Zhao²,

Gao³

et al. 2021

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

show abstract

“…Ma Xiaolian et al discussed the role of Nemothoracoplasty combined with magnesium sulfate injection in the clinical treatment of hypertensive disorders during pregnancy [29]. The results indicated that the overall effective rate in the combination group was 95.74%, significantly higher than the 82.22% in the magnesium sulfate group (P<0.05).…”

Section: Combined Use Of Multiple Drugsmentioning

confidence: 99%

Advancements in Pharmacological Treatment of Pregnancy-Induced Hypertension

2024

medbm

View full text Add to dashboard Cite

Pregnancy-induced hypertension (PIH) is a common obstetric disease characterized by clinical symptoms such as proteinuria, hypertension, and edema. It may even lead to heart and kidney failure, posing a serious threat to the life safety of pregnant women and neonates. Therefore, it is imperative to enhance hemodynamic monitoring for pregnant women and provide personalized prevention and treatment strategies. Medication plays a crucial role in managing pregnancy-induced hypertension, with diuretics, antihypertensive agents, and antispasmodics being the primary pharmacological interventions to improve the condition. This research, validated through literature review, focuses on the progress in drug research related to pregnancy-induced hypertension, aiming to contribute new insights to the clinical diagnosis and treatment of PIH.

show abstract

“…1,2 Not only does it contribute to the latter, but is also associated with prolonged chronic hypertension, renal failure, or neurological disorders, which may, in turn, contribute to most pregnancy-related health complications. [3][4][5] Research has established maternal mortality and morbidity as the worse health issue on a universal scale. Global estimations demonstrate that 287 000 women died from a maternal cause during 2020, which equates to about 800 maternal deaths per day.…”

Section: Introductionmentioning

confidence: 99%

Pregnancy-induced hypertension awareness, knowledge and its risk factors: A cross-sectional study

Peter,

Okafor

2024

Pak J Med Sci

View full text Add to dashboard Cite

Background and Objective: Pregnancy-induced hypertension (PIH) has severe implications for maternal morbidity and mortality; thus, boosting pregnant women’s awareness and knowledge of this medical condition is crucial for improving the mother’s and foetus’s health. This study assessed the awareness and knowledge of PIH and its risk factors among pregnant women in Mdantsane, South Africa. Methods: This cross-sectional study involved 249 conveniently selected and consenting pregnant women attending antenatal care clinics in Mdantsane, Buffalo City Metropolitan Municipality, South Africa. A self-designed questionnaire was utilised to collect data. Descriptive statistics, chi-square (χ2) test and multivariate logistic regression analysis were performed. The significance level was 0.05. Results: Over 50% of the women were knowledgeable about PIH and associated risk factors ((χ2=4.92; p = 0.04). The prevalence of PIH was 51.8%, and married women were more aware of the PIH risk factors (71.1%). Women with previous pregnancies were more likely to be aware of PIH (OR = 17.1, 95%; CI = 9.09 to 32.15) compared to first time mothers. Women in age group 36-45 were 2.5 times more likely to be aware of PIH (OR = 2.5, 95% CI: 1.19–3.24) compared to women aged <35 years. Likewise, women aged 36-45 years were two times more likely to be knowledgeable about risk factors for PIH (OR = 2.3, 95% CI: 1.14–2.81) compared to women aged <35 years. Married women were more likely to be aware of PIH risk factors (OR = 2.70, 95% CI = 1.35-5.47) than unmarried women. Moreover, pregnancy increases the likelihood (OR=12.8, 95% CI: 6.97-23.58) of being aware of PIH risk factors. There was a significant difference between the mean ages of women who knew about PIH risk factors and those who do not (t=3.49, Mean difference = 3.49, p=0.0001, 95% CI (2.54; 4.44)). Conclusion: The prevalence of PIH was high. Age, history of PIH, previous pregnancy, and marital status were predictors of PIH knowledge/awareness and risk factors for PIH. Context-specific health education programmes during prenatal visits are crucial to improving pregnant women’s knowledge of PIH. doi: https://doi.org/10.12669/pjms.40.4.8247 How to cite this: Peter BB, Okafor UB. Pregnancy-induced hypertension awareness, knowledge and its risk factors: A cross-sectional study. Pak J Med Sci. 2024;40(4):629-636. doi: https://doi.org/10.12669/pjms.40.4.8247 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

show abstract

Magnesium Sulfate in combination with Nifedipine in the treatment of Pregnancy-Induced Hypertension

Cited by 3 publications

References 16 publications

Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH

Clinical Evaluation of Pinggan Yiqi Yangshen Recipe Combined with Labetalol Hydrochloride and Magnesium Sulfate in the Treatment of PIH

Advancements in Pharmacological Treatment of Pregnancy-Induced Hypertension

Pregnancy-induced hypertension awareness, knowledge and its risk factors: A cross-sectional study

Contact Info

Product

Resources

About