Magnetic fluctuations affect circadian patterns of locomotor activity in zebrafish

Крылов, В. В.

doi:10.1101/2021.09.08.459369

Cited by 3 publications

(3 citation statements)

References 49 publications

(63 reference statements)

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“…Lighting conditions were reported in all studies in the review and strategies were evenly split with 14 studies (51.85%) using a regimen of 14/10 hours light/dark cycle and 13 (48.15%) with 12/12 hours light/dark cycle. This is an additional criterion to be standardized in other to optimize the evaluation of desired effects without the interference of the light/dark cycle since the circadian cycle has a direct impact on physiology and behavior (Kopp et al, 2018;Krylov et al, 2021).…”

Section: Ee Protocols In Zebrafishmentioning

confidence: 99%

Is environmental enrichment beneficial for laboratory animals? A systematic review of studies in zebrafish

Gallas‐Lopes

Benvenutti²,

Donzelli

et al. 2023

Preprint

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Environmental enrichment (EE) consists of a series of interventions that are carried out in the home environment to provide greater exposure to sensory stimuli with the objective of mimicking the natural habitat for the animals housed in the laboratory, offering a more complex environment like those found in nature. Some studies have shown the positive effects of EE on zebrafish housed in a laboratory environment. However, this evidence is still very recent and accompanied by contradictory results. Furthermore, there is great variability in the protocols applied, and in the conditions of the tests, tanks, and materials used for creating an EE environment. This substantial variability can bring many uncertainties to the development of future studies and hinder the reproducibility and replicability of research. In this context, the main objective of this study was to carry out a systematic review of the literature aiming to provide an overview of the EE protocols used in zebrafish. We conducted a systematic review following PRISMA recommendations. The literature search was performed in PubMed, Scopus, and Web of Science databases and the studies were selected based on inclusion/exclusion criteria. We performed data extraction and risk of bias analysis of the studies included. A total of 901 articles were identified in the databases and 27 of these studies were included in this review. Among these studies, the effect of EE was evaluated as two different proposals. (1) to improve animal welfare and (2) as an intervention for the prevention of some disorders. Although the zebrafish EE protocols presented a series of experimental differences, the results showed that the benefits of the EE for zebrafish were robust. According to the results described here, the use of EE in the zebrafish home tank provides better welfare and may reduce sources of bias in scientific experiments, such as high-stress levels and fighting events.

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Section: Ee Protocols In Zebrafishmentioning

confidence: 99%

Is environmental enrichment beneficial for laboratory animals? A systematic review of studies in zebrafish

Gallas‐Lopes

Benvenutti²,

Donzelli

et al. 2023

Preprint

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“…Behavioral diversity can be displayed in many forms including differences in overall activity, responses to stimuli, and social interactions 17,28 and is also highly prominent in diel rhythms of behavior 29,30 . Studies in terrestrial organisms, like drosophilid flies, identified differences in the expression of circadian clock genes and the neuropeptide pigmentdispersing factor (PDF) to be responsible for species-and population-specific patterns of diel activity 3,20,21,[31][32][33] .…”

Section: Introductionmentioning

confidence: 99%

Behavioral rhythms are bad predictors of general organismal rhythmicity

Häfker

Holcik

Vadiwala

et al. 2022

Preprint

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The 24 hour day/night cycle prominently controls behavior and physiology. Most diel behaviors are under circadian clock control, but behavioral rhythmicity also exhibits significant individual diversity. Even genetically identical clones raised under the same conditions can develop distinct behavioral mannerisms. While terrestrial model systems have provided key molecular insights, the variability and molecular basis of diel rhythms in marine animals are much less investigated, although critically informative for evolutionary and ecological hypotheses. Here we investigate the phenotypic diversity of diel locomotor rhythms in the marine annelid Platynereis dumerilii. Individual-specific diel activity patterns are maintained over time, but differ strongly even between co-raised siblings. Knock-out of pigment-dispersing factor (PDF), a neuropeptide central to diel rhythmicity in Drosophila melanogaster, reveals only limited contributions of PDF to rhythmic behavioral diversity. Diel transcriptomes sampled from behaviorally rhythmic versus arrhythmic worms show no differences in circadian core clock transcript oscillations. Instead, behaviorally rhythmic worms exhibit a distinct enrichment of cycling transcripts related to behavior and neuronal differentiation, while behaviorally arrhythmic worms show an enrichment of metabolic and transport-related diel-cycling transcripts. Cycling of matrix metalloproteinases suggests that individual rhythmicity may be influenced via extracellular matrix remodeling and neuropeptide processing. Our results emphasize that organismal rhythmicity is highly complex and not necessarily properly reflected by a single read-out (like behavior or clock gene expression). We hypothesize that diversity in diel behavioral patterns allows for an adjustment to (micro)habitat conditions in the wild, thereby impacting on population fitness and adaptability to changing environmental conditions.

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“…Similarly, the exposure of larvae to the same magnetic fields between 11 and 14 days post fertilization led to the desynchronization of Cry1aa and Per1b circadian oscillations [ 22 ]. Moreover, preliminary data on the entraining of zebrafish circadian rhythms by magnetic oscillations with a period of 26.8 h are available [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Influence of Geomagnetic Disturbances at Different Times of Day on Locomotor Activity in Zebrafish (Danio Rerio)

Крылов

2021

Clocks & Sleep

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The influence of magnetic fields and natural geomagnetic storms on biological circadian rhythms are actively studied. This study reveals an impact of local natural perturbations in the geomagnetic field that occurred at different times of the day on circadian patterns of locomotor activity of zebrafish. A decrease in zebrafish swimming speed was observed during the geomagnetic disturbances before or after the fluctuations of diurnal geomagnetic variation. However, if the geomagnetic perturbations coincided with the fluctuations of diurnal geomagnetic variation, the decrease in zebrafish swimming speed was insignificant. This result suggests that the biological effects of geomagnetic disturbances may depend on synchronization with the diurnal geomagnetic variation. It implies that the previously published correlations between geomagnetic activity and medical or biological parameters could result from a disruption in circadian biorhythms.

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Magnetic fluctuations affect circadian patterns of locomotor activity in zebrafish

Cited by 3 publications

References 49 publications

Is environmental enrichment beneficial for laboratory animals? A systematic review of studies in zebrafish

Is environmental enrichment beneficial for laboratory animals? A systematic review of studies in zebrafish

Behavioral rhythms are bad predictors of general organismal rhythmicity

Influence of Geomagnetic Disturbances at Different Times of Day on Locomotor Activity in Zebrafish (Danio Rerio)

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