Magnetic nanoparticles for a new drug delivery system to control quercetin releasing for cancer chemotherapy

Barreto, A. L. H.; Santiago, Vívian Romero; Mazzetto, Selma Elaine; Denardin, Juliano C.; Lavín, R.; Mele, Giuseppe; Ribeiro, Maria Elenir Nobre Pinho; Vieira, Ícaro Gusmão Pinto; Gonçalves, Tamara; Ricardo, Nágila M.P.S.; Fechine, Pierre Basílio Almeida

doi:10.1007/s11051-011-0559-9

Cited by 68 publications

(54 citation statements)

References 28 publications

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“…They were polydispersed and most of them agglomerated due to interparticle magneto-dipole interactions. This kind of behavior has been previously observed in other studies (Barreto et al 2011;Zhao et al 2009;Rao et al 2007;Wang et al 2003). Figure 6d- nanoparticles kept the original rough spherical shape and, furthermore, grain sizes agglomerates were evident as well.…”

Section: Transmission Electron Microscopy (Tem)supporting

confidence: 86%

Novel ferrofluids coated with a renewable material obtained from cashew nut shell liquid

Barreto

Maia

Santiago

et al. 2011

Microfluid Nanofluid

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In this work, we present the synthesis and characterization of a new surfactant molecule obtained from a byproduct of the cashew nut processing (diphosphorylated cardol, DPC). It is herein used to overcoat magnetic nanoparticles showing spinel structures in order to create new ferrofluids. The nanoparticle structure and magnetic properties have been deeply investigated. DPCfunctionalized Fe 3 O 4 and NiFe 2 O 4 samples exhibit higher magnetic saturation than DPC-CoFe 2 O 4 . These new ferrofluids reveal appealing as possible nanoparticle stabilizing molecules, magnetic resonance imaging agents, storage systems or in any material science field that requires the employment of biocompatible magnetic stable fluids.

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Section: Transmission Electron Microscopy (Tem)supporting

confidence: 86%

Novel ferrofluids coated with a renewable material obtained from cashew nut shell liquid

Barreto

Maia

Santiago

et al. 2011

Microfluid Nanofluid

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“…FTIR analysis is one of the most important techniques for a quick and efficient identification of encapsulated chemical molecules [13,24]. In Figure 3a, it was observed characteristic bands of Fe-O around 560–580 cm −1 for Fe 3 O 4 as the main phase of spinel ferrites and corresponds to stretching vibration in tetrahedral site [25,26].…”

Section: Resultsmentioning

confidence: 99%

“…For these applications, the particles must have high magnetic saturation, biocompatibility and interactive surface functionalities [13]. Studies in vivo have shown that Fe 3 O 4 nanoparticles are relatively safe, as they do not accumulate in the vital organs and are rapidly eliminated from the body [14,15].…”

Section: Introductionmentioning

confidence: 99%

Magnetic Nanosystem for Cancer Therapy Using Oncocalyxone A, an Antitomour Secondary Metabolite Isolated from a Brazilian Plant

Barreto

Santiago

Freire

et al. 2013

IJMS

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This paper describes the investigation and development of a novel magnetic drug delivery nanosystem (labeled as MO-20) for cancer therapy. The drug employed was oncocalyxone A (onco A), which was isolated from Auxemma oncocalyx, an endemic Brazilian plant. It has a series of pharmacological properties: antioxidant, cytotoxic, analgesic, anti-inflammatory, antitumor and antiplatelet. Onco A was associated with magnetite nanoparticles in order to obtain magnetic properties. The components of MO-20 were characterized by XRD, FTIR, TGA, TEM and Magnetization curves. The MO-20 presented a size of about 30 nm and globular morphology. In addition, drug releasing experiments were performed, where it was observed the presence of the anomalous transport. The results found in this work showed the potential of onco A for future applications of the MO-20 as a new magnetic drug release nanosystem for cancer treatment.

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“…The quercetin-magnetite nanoparticles (Fe 3 O 4 ) system was incorporated into a triblock copolymer of ethylene oxide and oxyphenylethylene, as a model of drug carrier system for anticancer agents [121].…”

Section: Organic/inorganic Hybrid Nanosystemsmentioning

confidence: 99%

Flavonoid Complexes as Promising Anticancer Metallodrugs

Uivaroşi¹,

Arbănași²

2017

Flavonoids - From Biosynthesis to Human Health

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Flavonoid metal complexes commonly exhibit an improvement of biological activity compared to the parent ligands. This chapter is focused on the antioxidant and anticanccer properties of flavonoid metal complexes, in correlation with their binding ability to vital macromolecules such as nucleic acids and serum proteins. Perspectives for an adequate formulation of these complexes were also discussed.

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Magnetic nanoparticles for a new drug delivery system to control quercetin releasing for cancer chemotherapy

Cited by 68 publications

References 28 publications

Novel ferrofluids coated with a renewable material obtained from cashew nut shell liquid

Novel ferrofluids coated with a renewable material obtained from cashew nut shell liquid

Magnetic Nanosystem for Cancer Therapy Using Oncocalyxone A, an Antitomour Secondary Metabolite Isolated from a Brazilian Plant

Flavonoid Complexes as Promising Anticancer Metallodrugs

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