2001
DOI: 10.1016/s0887-8994(01)00306-x
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Magnetic resonance imaging in three children with kernicterus

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Cited by 70 publications
(38 citation statements)
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“…Kernicteric injury at term has been confirmed with MRI (Table 2). T2-weighted images permitted recognition of gliosis in globus pallidus [17][18][19][20][21][22][23][24][25] and subthalamic nucleus 21,24 after 6 months of age. Pallidal involvement, if partial, affects the medial posterior and inferior area of the nucleus.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Kernicteric injury at term has been confirmed with MRI (Table 2). T2-weighted images permitted recognition of gliosis in globus pallidus [17][18][19][20][21][22][23][24][25] and subthalamic nucleus 21,24 after 6 months of age. Pallidal involvement, if partial, affects the medial posterior and inferior area of the nucleus.…”
Section: Discussionmentioning
confidence: 99%
“…24,27 The discernibility of pallidum on T2-weighted images in the hyperacute stage is unusual and helpful only in association with relative increase of intensity on T1. 28 Manganese intoxication is very unlikely in these newborns and would have caused transient T1 hyperintensity without leaving permanent T2 hyperintensity in case 1 with liver disease.…”
Section: Discussionmentioning
confidence: 99%
“…19 Choreoathetosis, and the classical MRI findings of kernicterus at follow-up, were documented in two preterm infants of 31 and 34 weeks gestation. 20 Neither of these infants was acutely ill in the newborn period and their peak TSB levels were 13.1 mg dl À1 (224 mmol l À1 ) and 14.7 mg dl À1 (251 mmol l À1 ) respectively.…”
Section: Introductionmentioning
confidence: 88%
“…[13][14][15] In past decades, autopsy proven kernicterus was reported in sick, very low birth weight infants who were exposed to low TSB levels (the so-called 'low bilirubin kernicterus') 16,17 and recent case series document that this remains a clinical risk. [18][19][20][21] In a recent study from the Netherlands, 18 5 sick, preterm infants (25 to 29 weeks gestation) with peak TSB levels ranging from 8.7 to 11.9 mg dl À1 (148 to 204 mmol l À1 ) developed the classical MRI findings of kernicterus. Serum albumin levels in these infants were strikingly low, ranging from 1.4 to 2.1 g dl À1 .…”
Section: Introductionmentioning
confidence: 99%
“…Entretanto, em 2001, Sugama et al 5 questionaram a rara ocorrência de encefalopatia bilirrubínica em prematuros, ao detectarem kernicterus em dois pacientes de 31 e 34 semanas de idade gestacional, respectivamente com bilirrubinemia de 13,1 e 14,7 mg/dl, sendo que nenhum deles apresentava sintomatologia sugestiva da doença no período neonatal. O primeiro caso tinha quadro de paralisia cerebral atetóide aos 3 anos de idade, e o segundo não sustentava a cabeça aos 7 meses e tinha hipotonia de tronco.…”
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