Magnetic Resonance Imaging White Matter Hyperintensities and Mechanism of Ischemic Stroke

Abstract

Background and Purpose-We sought to determine the relations between infarct subtype and white matter hyperintensities (WMHIs) on MRI. Materials and Methods-We studied 395 ischemic stroke patients with 1.0-T MRI. The number of lacunar, border-zone, and cortical infarcts was registered. WMHIs were analyzed in 6 areas. Univariate and multivariate statistical analyses were used to find the risk factors for different infarct subtypes and to study the connections between WMHIs and brain infarcts. Results-Lacunar

Classification of White Matter Lesions on Magnetic Resonance Imaging in Elderly Persons

“…The subtype of ischemic strokes has been found to be differentially associated with the type of WML. PVWML was a predictor for the border-zone infarcts especially around the posterior horns, whereas DWML was a predictor for lacunar infarcts (54). High plasma homocysteine level which had been reported to be a risk factor for small vessel disease (SVD) (55) was related to increased DWML but not to PVWML in both normal elderly and AD patients (56,57).…”

Cerebral Small Vessel Disease and Kidney Function Predict Long-Term Survival in Patients With Acute Stroke

“…Four hundred eighty-six of the living patients were included in the cohort. 25 Of these, 383 (78.9%) had data on both serum creatinine level and MRI. Of these, patients with low eGFR (Nϭ5 [1.3%]; Ͻ30 mL/min/1.73 m 2 ) were excluded from the analysis and the final cohort consisted of 378 patients.…”

Incidental Acute Infarcts Identified on Diffusion-Weighted Images: A University Hospital-Based Study: Fig 1.

“…5 These predisposing factors are also found in patients with lacunar infarcts; thus, it has been proposed that leukoaraiosis and symptomatic lacunar infarcts share a similar underlying vasculopathy, namely, subcortical occlusive small-vessel disease secondary to arteriolosclerosis. [7][8][9] Population studies have noted that leukoaraiosis progresses over a period of years. 6,10 The mechanism by which these lesions increase over time remains unknown.…”