Magnetic stirring-assisted dispersive liquid–liquid microextraction followed by high performance liquid chromatography for determination of phthalate esters in drinking and environmental water samples

Ranjbari, Elias; Hadjmohammadi, Mohammad Reza

doi:10.1016/j.talanta.2012.08.019

Cited by 69 publications

(38 citation statements)

References 37 publications

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“…These methods suffer from high consumption of organic solvents and relatively long processing time. To cover these drawbacks, several sample preparation techniques have been developed including solid-phase microextraction, 14 hollow fiber-liquid phase microextraction, 15 solidification of floating drop microextraction, 16 single drop microextraction, 17 vortex-assisted and ultrasound-assisted emulsification liquid-liquid microextraction (USAEME), 18 dispersive liquid-liquid microextraction (DLLME), [19][20][21] air-assisted liquid-liquid microextraction, 22 ionic liquids in dispersive liquid-liquid microextraction 23,24 and solid-phase extraction (SPE).…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of Ultrasound Assisted and Dispersive Liquid-Liquid Microextractions Combined with HPLC-UV Method for Determination of Bosentan in Human Plasma and Urine

Sajedi-Amin

Asadpour‐Zeynali

Khoubnasabjafari

et al. 2016

J. Braz. Chem. Soc.

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A feasible, rapid, sensitive and reliable dispersive liquid-liquid microextraction (DLLME) and ultrasonic assisted liquid-liquid microextraction (USAEME) combined with high-performance liquid chromatography (HPLC) method with UV detection was developed and validated for analysis of bosentan in human plasma and urine samples. All validation tests were reported according to FDA guidelines. Since chromatographic methods are precise, accurate and provide excellent separation are increasingly being used in determination of trace amount of drugs in biological goals. So the optimized experimental extraction factors from our previous work were used to evaluate HPLC-UV method for decreasing the limit of quantifications (LOQs) to cover the therapeutic range. Simple centrifugation of urine samples was sufficient prior to microextraction procedure, while acetonitrile protein precipitation provides sample clean up for plasma samples. The suggested method was linear (correlation coefficient R 2 > 0.998) over a range of 0.1-10 μg mL -1 which covers the therapeutic range. Proposed methods are practical for quantitative analysis of bosentan in real samples, and could be used in routine clinical analyses.

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Section: Introductionmentioning

confidence: 99%

Development and Validation of Ultrasound Assisted and Dispersive Liquid-Liquid Microextractions Combined with HPLC-UV Method for Determination of Bosentan in Human Plasma and Urine

Sajedi-Amin

Asadpour‐Zeynali

Khoubnasabjafari

et al. 2016

J. Braz. Chem. Soc.

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“…Due to differences in the physicochemical properties of PAEs, gradient elution is generally necessary and methanol-water containing a small amount of formic acid or acetic acid commonly serves as the mobile phase [11,22]. Acetonitrile often substitutes for methanol due to its lower cut-off wavelength, lower viscosity coefficient and higher elution ability [122].…”

Section: Separationmentioning

confidence: 99%

Recent advances in analysis of phthalate esters in foods

Yang

Wang

et al. 2015

TrAC Trends in Analytical Chemistry

131

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“…To determine the plasticizers in water samples, gas chromatography (GC) (8,9), gas chromatographymass spectrometry (GC-MS) (7,10,11) and highperformance liquid chromatography (HPLC) (12)(13)(14) have been used. Nevertheless, when the concentration levels are low, a previous enrichment step is usually needed.…”

Section: Introductionmentioning

confidence: 99%

“…(SFDME) (7), single drop microextraction (SDME) (8), vortex-assisted surfactant-enhancedemulsification liquid-liquid microextraction (10), dispersive liquid-liquid microextraction (DLLME) (11)(12)(13)(14), and solid-phase extraction (SPE) (15).…”

mentioning

confidence: 99%

Investigation of Di-ethylhexyl Phthalate Migration by Applying Magnetic Solid Phase Extraction Method Followed by GC-FID Determination

Faraji¹,

Adeli

2016

Nutr Food Sci Res

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A B S T R A C T Background and Objectives:The addition of plasticizers (mainly phthalates and adipates) makes plastic flexible and popular for packaging, storing and preserving food, water, and so on. The most widely used plasticizer in food contact applications is di-ethylhexyl phthalate (DEHP) though being suspected to have carcinogenic and estrogenic properties. The aim of this study is application of magnetic solid phase extraction as new absorbent for determination of DEHP in water samples by gas chromatography (GC). Materials and Methods:Important factors in extraction, separation and determination processes were optimized using the one-variable-at-a-time method. For optimization, all tests were performed two times.Figures of merit of the proposed method were evaluated. The amount of DEHP in some water samples was determined using the proposed method. Results:The results showed that the obtained chromatogram of extract was free of significant interference. The preservatives' recoveries ranged from 91.6% to 102.2%. Limit of detection and limit of quantitation were 0.1 mg kg -1 and 0.3 µg L -1 , respectively. Concentration of DEHP in the studied samples was in the range of N.D-2.3 µg L -1 . Conclusions:The acceptable performance and reliability of the proposed method were demonstrated. Temperature and time were fount as the most effective parameters in migration of DEHP.

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Magnetic stirring-assisted dispersive liquid–liquid microextraction followed by high performance liquid chromatography for determination of phthalate esters in drinking and environmental water samples

Cited by 69 publications

References 37 publications

Development and Validation of Ultrasound Assisted and Dispersive Liquid-Liquid Microextractions Combined with HPLC-UV Method for Determination of Bosentan in Human Plasma and Urine

Development and Validation of Ultrasound Assisted and Dispersive Liquid-Liquid Microextractions Combined with HPLC-UV Method for Determination of Bosentan in Human Plasma and Urine

Recent advances in analysis of phthalate esters in foods

Investigation of Di-ethylhexyl Phthalate Migration by Applying Magnetic Solid Phase Extraction Method Followed by GC-FID Determination

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