Magnetoliposomes with size controllable insertion of magnetic nanoparticles for efficient targeting of cancer cells

Choi, Won Il; Sahu, Abhishek; Wurm, Frederik R.; Jo, Seong‐Min

doi:10.1039/c9ra02529d

Cited by 26 publications

(27 citation statements)

References 39 publications

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“…[ 156 ] Other studies have used a solvent‐guided method for incorporating larger MNPs (mean diameter ∼10 nm) into phospholipid bilayers. [ 157 ] They solved the low insertion efficiency of the hydration method with chloroform as a supporting agent guide. [ 157 ] These magnetic liposomes (MLs) were modified with the human epidermal receptor 2 (HER2) antibody and tested for cell isolation for drug delivery.…”

Section: Biomedical Applications Of Mnpsmentioning

confidence: 99%

“…[ 157 ] They solved the low insertion efficiency of the hydration method with chloroform as a supporting agent guide. [ 157 ] These magnetic liposomes (MLs) were modified with the human epidermal receptor 2 (HER2) antibody and tested for cell isolation for drug delivery. [ 157 ] A 75% isolation efficiency was observed in specific cell lines.…”

Section: Biomedical Applications Of Mnpsmentioning

confidence: 99%

“…[ 157 ] These magnetic liposomes (MLs) were modified with the human epidermal receptor 2 (HER2) antibody and tested for cell isolation for drug delivery. [ 157 ] A 75% isolation efficiency was observed in specific cell lines. [ 157 ] These MLs were further modified with folate and the capacity of isolation was also tested.…”

Section: Biomedical Applications Of Mnpsmentioning

confidence: 99%

“…[ 157 ] A 75% isolation efficiency was observed in specific cell lines. [ 157 ] These MLs were further modified with folate and the capacity of isolation was also tested. [ 157 ] These results suggest that these large MNPs can be used to detect and analyze freely circulation tumor cells.…”

Section: Biomedical Applications Of Mnpsmentioning

confidence: 99%

“…[ 157 ] These MLs were further modified with folate and the capacity of isolation was also tested. [ 157 ] These results suggest that these large MNPs can be used to detect and analyze freely circulation tumor cells. [ 157 ] Lu et al., proposed thermosensitive liposome with MNPs and Camptosar.…”

Section: Biomedical Applications Of Mnpsmentioning

confidence: 99%

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Recent progress of magnetic nanoparticles in biomedical applications: A review

et al. 2021

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Magnetic nanoparticles (MNPs) offer tremendous potentialities in biomedical applications for a long while. Since these materials' interactions in biological media largely rely on their crystal structures, sizes, and shapes, detailed studies on their synthesis mechanism for medicinal aspects are crucial. Despite many review reports that have already been published on MNPs, they mainly have focused either on their perspective in biomedical applications or their synthesis and characterization along with functionalization mechanisms as individual entities. For this reason, this review uncovers a comprehensive insight into the ongoing improvement of fabrication processes, surface functionalization of MNPs for biomedical applications together. Besides, various magnetic nanocomposite (MNCs) for smart drug delivery, recent hyperthermia treatment, lab‐on‐a‐chip, and magnetic bio‐separation, and some of the recent emerging imaging techniques using MNPs are discussed. A detailed analysis of toxicity, challenges, and recent progress of clinical trials of MNPs is sketched out to open numerous entryways for advanced research on MNPs for biomedical applications.

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Section: Biomedical Applications Of Mnpsmentioning

confidence: 99%