Mainstream smoke constituent yields and predicting relationships from a worldwide market sample of cigarette brands: ISO smoking conditions

Candy Flavorings in Tobacco

“…However, even when examined within individuals not changing brands, differences in levels of one biomarker do not reliably predict quantitative differences in other biomarkers (6). Comparisons across brands are also complicated by the differences in composition of the smoke generated, and presumably the exposures that result, with different brands of cigarettes (70). As an example, an experimental switching study to a PREP demonstrated that reductions in one biomarker do not necessarily predict that other biomarkers will also be reduced (27).…”

Tobacco smoke particulate matter chemistry by NMR

“…Other smoke constituents suggested by the spectra are styrene, polycyclic aromatic hydrocarbons, hydroquinone, and triacetin; all of these have been found in cigarette smoke by other methods. 11 Triacetin is known to be present in cigarette filters. 12 The NMR line intensities for geraniol and triacetin in one sample of PM MTS from brand D (filtered) cigarettes indicated levels of about 4 and 7 µg mg 1 in the PM MTS , respectively; the presence and approximate levels of the two compounds were confirmed by GC/MS.…”

Tracheobronchial and Alveolar Particle Surface Area Doses in Smokers

“…Such a high lung cancer risk is due to the physical-chemical characteristics of the mainstream cigarette smoke (MSS). In fact, the cigarette-generated particles contain more than 3500 semi-volatile and non-volatile compounds, some of them classified as carcinogenic such as hydrocarbons (PAHs; [24][25][26][27]), dioxins and furans [28], heavy metals [25,[29][30][31][32][33][34], and tobacco-specific nitrosamines [25,31,[35][36][37]. Moreover, in fresh unaged tobacco cigarette mainstream smoke particle concentrations of about 4 × 10 9 part cm −3 were measured, with an arithmetic mean diameter of about 0.2 µm [38][39][40][41].…”