Major Pulmonary Resection for Suspected but Unconfirmed Malignancy

Keagy, Blair A.; Starek, Peter J.K.; Murray, Gordon F.; Battaglini, James W.; Lores, M. E.; Wilcox, Benson R.

doi:10.1016/s0003-4975(10)62278-3

Cited by 50 publications

(13 citation statements)

References 18 publications

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“…Ciò spiega, in parte, perché approssimativamente il 50% di noduli indeterminati sottoposti a trattamento chirurgico risultano benigni [12][13][14].…”

Section: Discussionunclassified

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Three–dimensional analysis of pulmonary nodules by MSCT with Advanced Lung Analysis (ALA1) software

et al. 2006

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Three-dimensional volume measurement with ALARiassunto 1 software is reproducible for all nodules as regards dimension and site. ALA-1 software provided a good and reproducible volume measurement in well-circumscribed and most juxtavascular nodules. Volumetric evaluation and reproducibility of volume estimation in juxtapleural pulmonary nodules, particularly those adjacent to diaphragmatic pleura, is inadequate, and software improvement is needed.

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“…Ciò spiega, in parte, perché approssimativamente il 50% di noduli indeterminati sottoposti a trattamento chirurgico risultano benigni [12][13][14].…”

Section: Discussionunclassified

“…This in part accounts for the approximately 50% of indeterminate nodules that are found to be benign after surgical excision [12][13][14]. Moreover, hospitalisation for surgical removal of an SPN costs around US$ 25,000 [15], so that the aim of treatment is to find a balance between early and unnecessary resections.…”

Section: Discussionmentioning

confidence: 99%

Three–dimensional analysis of pulmonary nodules by MSCT with Advanced Lung Analysis (ALA1) software

et al. 2006

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“…In both the United States and Europe, approximately half of the patients undergoing surgical biopsy of an indeterminate lung nodule subsequently received a diagnosis that the nodule was benign (26)(27)(28)(29). A benign biopsy rate of 50% would be extraordinarily costly and carry with it morbidity and mortality that would preclude use of this screening technique.…”

Section: False-positive Ratesmentioning

confidence: 99%

Screening for Lung Cancer with Low-Dose Spiral Computed Tomography

Swensen

Jett

Sloan

et al. 2002

Am J Respir Crit Care Med

631

413

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Studies suggest that screening with spiral computed tomography can detect lung cancers at a smaller size and earlier stage than chest radiography can. To evaluate low-radiation-dose spiral computed tomography and sputum cytology in screening for lung cancer, we enrolled 1,520 individuals aged 50 yr or older who had smoked 20 pack-years or more in a prospective cohort study. One year after baseline scanning, 2,244 uncalcified lung nodules were identified in 1,000 participants (66%). Twenty-five cases of lung cancer were diagnosed (22 prevalence, 3 incidence). Computed tomography alone detected 23 cases; sputum cytology alone detected 2 cases. Cell types were: squamous cell, 6; adenocarcinoma or bronchioalveolar, 15; large cell, 1; small cell, 3. Twenty-two patients underwent curative surgical resection. Seven benign nodules were resected. The mean size of the non-small cell cancers detected by computed tomography was 17 mm (median, 13 mm). The postsurgical stage was IA, 13; IB, 1; IIA, 5; IIB, 1; IIIA, 2; limited, 3. Twelve (57%) of the 21 non-small cell cancers detected by computed tomography were stage IA at diagnosis. Computed tomography can detect early-stage lung cancers. The rate of benign nodule detection is high.

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“…There is a lot of literature on the difficulties of this differential diagnosis [6,11,12,15]. CT of the chest is increasingly used in the surveillance of oncology patients for lung metastasis and is more beneficial than conventional radiography or tomography in distinguishing the benign from the malignant form.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Nodules Simulating Metastasis of Germ Cell Tumor after Aggressive Chemotherapy

et al. 1988

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We describe a patient in whom pulmonary nodules developed without infectious symptoms during treatment with bleomycin, cis-platinum, vinblastine and etoposide combination chemotherapy for metastatic extragonadal germ cell tumor. At thoracotomy only fibrosis was found. In this case, false-positive elevation of Α-fetoprotein and the CT scan appearance made us interpret the pulmonary nodules as new metastatic lesions.

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Major Pulmonary Resection for Suspected but Unconfirmed Malignancy

Cited by 50 publications

References 18 publications

Three–dimensional analysis of pulmonary nodules by MSCT with Advanced Lung Analysis (ALA1) software

Three–dimensional analysis of pulmonary nodules by MSCT with Advanced Lung Analysis (ALA1) software

Screening for Lung Cancer with Low-Dose Spiral Computed Tomography

Pulmonary Nodules Simulating Metastasis of Germ Cell Tumor after Aggressive Chemotherapy

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