Making a Pragmatic Choice for Fluid Resuscitation in Critically Ill Patients

Seymour, Christopher W.; Angus, Derek C.

doi:10.1001/jama.2013.280503

Cited by 15 publications

(6 citation statements)

References 20 publications

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“…Mortality at day 90 was added as a secondary outcome measure during the trial and was observed to be lower in the colloid vs. crystalloid group. However, the data should be interpreted with caution, as stated in the editorial accompanying the publication, in particular as the trial results come at high risk of bias (unblinded, uncertain allocation concealment and marked baseline imbalance) …”

Section: Discussionmentioning

confidence: 99%

Acute kidney injury with hydroxyethyl starch 130/0.42 in severe sepsis

Müller

Haase

Lange

et al. 2014

Acta Anaesthesiol Scand

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Section: Discussionmentioning

confidence: 99%

Acute kidney injury with hydroxyethyl starch 130/0.42 in severe sepsis

Müller

Haase

Lange

et al. 2014

Acta Anaesthesiol Scand

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“…However, the trial had high risk of bias in several domains (unblinded, uncertain allocation concealment and baseline imbalance) and the results differed from those of the high‐quality trials mentioned above. In an accompanying editorial, the editor argued for cautious interpretation of these findings and that crystalloid should be the first line fluid in patients with shock . Given the high risk of bias in CRISTAL, we did not take these data into consideration.…”

Section: Resultsmentioning

confidence: 82%

Scandinavian clinical practice guideline on choice of fluid in resuscitation of critically ill patients with acute circulatory failure

Perner

Junttila²,

Haney

et al. 2014

Acta Anaesthesiol Scand

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Background The task force on Acute Circulatory Failure of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine produced this guideline with recommendations concerning the use of crystalloid vs. colloid solutions in adult critically ill patients with acute circulatory failure. Methods Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to grade the quality of evidence and to determine the strengths of the recommendations. As efficacy and harm may vary in different subpopulations of patients with acute circulatory failure, we produced recommendations for general intensive care unit (ICU) patients and those with sepsis, trauma and burn injury. Results For general ICU patients and those with sepsis, we recommend using crystalloids for resuscitation rather than hydroxyethyl starch and we suggest using crystalloids rather than gelatin and albumin. For patients with trauma we recommend to use crystalloids for resuscitation rather than colloid solutions. For patients with burn injury we provide no recommendations as there are very limited data from randomised trials on fluid resuscitation in this patient population. Conclusions We recommend using crystalloid solutions rather than colloid solutions for resuscitation in the majority of critically ill patients with acute circulatory failure.

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“…8 Further research has indicated that the choice of fluid used to resuscitate patients with hypovolemia should be selected based on a patient-to-patient basis. 31 Another randomized control trial in 2007 investigated whether using PPV to guide volume resuscitation during surgery would improve postoperative outcomes. The authors concluded that minimizing changes in PPV by fluid loading decreased the incidence of postoperative complications.…”

Section: Discussionmentioning

confidence: 99%