Making In Vitro Tumor Models Whole Again (Adv. Healthcare Mater. 14/2023)

Abstract

In Vitro Tumor Models The success of personalized cancer therapy hinges on a timely clinical decision and a preclinical model that can recapitulate tumor and stromal heterogeneity for clinically relevant drug profiling. In article 2202279, Eliza Li Shan Fong and co‐workers review how by transcending the existential reductionist approaches, bioengineered patient‐derived explant (PDE) models can truly replicate the tumor features in vivo and allow clinicians to rapidly offer and strategize specific care and treatment for each cancer patient.