Malignant abdominal masses in children: quick guide to evaluation and diagnosis

Golden, Carla; Feusner, James

doi:10.1016/s0031-3955(02)00098-6

Cited by 58 publications

(25 citation statements)

References 92 publications

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“…When a malignant lesion is suspected, CT scan of the chest, abdomen, and pelvis can be done to determine mass extension and infiltration into adjacent organs and vessel' with 'look for distant metastases. (2,3) Neuroblastoma is the most common abdominal malignancy in infants. (4) Wilms tumor is the second most common pediatric malignant abdominal tumor and the most common primary pediatric renal malignancy.…”

Section: Discussionmentioning

confidence: 99%

Role of Multidetector Computed Tomography in Evaluation of Pediatric Abdominal Tumors

Nagaraju¹,

Bhimarao²

2015

jemds

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BACKGROUND:A wide variety of tumors may affect pediatric abdomen, which arise from various organs. These may be benign or malignant. OBJECTIVES: (1) To assess the role of computed tomography in the evaluation of pediatric abdominal tumors-in localization and characterization. (2) To illustrate the common pediatric abdominal masses. MATERIALS AND METHODS: 30 patients in the age group 0 to 18 years with suspected abdominal mass underwent non contrast and contrast enhanced computed tomography. The lesions were evaluated in terms of location, organ of origin, CT characters (Including attenuation, enhancement, Presence of necrosis, cystic changes and calcifications) and extensions. Based on the age of the patient and the CT characters, provisional and differential diagnoses were given. These were correlated with the final diagnosis obtained after surgical and histopathological examination and the sensitivity of CT in locating and characterizing various abdominal masses was calculated. RESULTS: Majority of patients in our study belonged to infantile age group (<1 year). Neuroblastomas were the most common tumor in our study followed by Wilms' tumor. Based on organ of origin, adrenal was the commonest organ of origin, followed by kidney and liver. Malignant tumors outnumbered benign tumors by 2:1. Multidetector computed tomography was an excellent imaging modality in localizing and characterizing these tumors. It had a diagnostic accuracy of 96.3% and was 100 % sensitive in detecting calcifications. It thus helped in narrowing differential diagnosis and in most cases helped in providing a provisional diagnosis close to final histopathological diagnosis. It also helped to provide details of extensions and mass effect of these tumors, with local involvements and distant metastases, which in turn were very important in planning further management. CONCLUSIONS: Multidetector computed tomography (MDCT) is a very sensitive imaging modality. It is fast, reliable, significantly accurate method for localizing and characterizing various tumors arising from pediatric abdomen. It helps in narrowing differentials and arriving at a final diagnosis in most cases. It also provides significant information for operative management.

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Section: Discussionmentioning

confidence: 99%

Role of Multidetector Computed Tomography in Evaluation of Pediatric Abdominal Tumors

Nagaraju¹,

Bhimarao²

2015

jemds

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“…O tumor abdominal é responsá-vel por cerca de 65% dos casos, sendo a glândula adrenal o principal local acometido, seguido por cavidade torácica, região cervical e gânglios simpáticos pélvicos (4) . Habitualmente observa-se uma massa sóli-da, nodular, palpável no flanco ou na linha média que provoca desconforto abdominal (5) . Os sítios metastáticos mais frequentes são os ossos longos, crânio, medula ós- sea, fígado, linfonodos e pele (6) .…”

Section: Discussionunclassified

Neuroblastoma com metástase orbitária

Torturella¹,

Figueiredo²,

Júnior³

et al. 2011

Rev. bras.oftalmol.

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“…Adrenal disorders in children have a wide variety of causes such as adrenal hemorrhage, neuroblastoma, pheochromocytoma, adenoma, adrenocortical carcinoma, and Wolman disease [1]. Neuroblastoma is the most common malignant abdominal tumor in children less than 5 years of age and accounts for 15% of all cancer-related deaths in children [2]. It is a tumor of neural crest cells and originates most frequently from the abdomen (retroperitoneum) as its primary site [2], with over half of the abdominal cases arising in the adrenal gland [3].…”

Section: Discussionmentioning

confidence: 99%

“…Neuroblastoma is the most common malignant abdominal tumor in children less than 5 years of age and accounts for 15% of all cancer-related deaths in children [2]. It is a tumor of neural crest cells and originates most frequently from the abdomen (retroperitoneum) as its primary site [2], with over half of the abdominal cases arising in the adrenal gland [3]. The malignancy should be considered ''heterogeneous'' in that the prognosis ranges from near uniform survival to high risk for death, depending on a variety of prognostic factors [3].…”

Section: Discussionmentioning

confidence: 99%

Sudden death due to adrenal neuroblastoma: child abuse mimic?

Park

Prahlow

2010

Forensic Sci Med Pathol

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Neuroblastoma is one of the most common malignancies in children. It is a tumor that can clinically present with varied symptoms that can mimic other entities, including child abuse. It is important that forensic pathologists are aware of the diseases that can masquerade as child abuse. A case of sudden, unexpected death in a 2-year-old due to previously undiagnosed neuroblastoma is presented. At initial presentation of the child in the emergency department, child abuse was considered as a possible explanation for the sudden demise. Death occurred before a full clinical workup could be completed and an autopsy was performed which unveiled the cause of death.

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Malignant abdominal masses in children: quick guide to evaluation and diagnosis

Cited by 58 publications

References 92 publications

Role of Multidetector Computed Tomography in Evaluation of Pediatric Abdominal Tumors

Role of Multidetector Computed Tomography in Evaluation of Pediatric Abdominal Tumors

Neuroblastoma com metástase orbitária

Sudden death due to adrenal neuroblastoma: child abuse mimic?

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