Malignant eccrine poroma invading the parotid gland

Abstract

Malignant eccrine poroma was first described by Pinkus and Mehregon in 1963. Because of the histologic characteristics of the tumor, these authors concluded that the tumor was likely of eccrine origin. Malignant eccrine poroma originates from the intraepidermal ductal portion of the eccrine gland. Like other tumors of skin adnexa, malignant eccrine poroma is a rare tumor. It mostly affects older persons. Clinical diagnosis is difficult, and lesions are often mistakenly identified as squamous cell carcinoma or pyogenic granuloma. We report a case of malignant eccrine poroma invading the parotid gland. A 65-year-old man presented with an ulcerated mass (2x3 cm) below the ear lobule of 3 months' duration. The mass was fixed to the skin and underlying parotid gland. The lesion was treated using a superficial parotidectomy approach including the overlying skin. Simultaneous neck dissection was performed. The diagnosis was malignant eccrine poroma invading the parotid gland.

Eccrine porocarcinoma of the head and neck: Meta‐analysis of 120 cases

“…Tumor cells often reveal mature duct formation including eosinophilic luminal cuticle or contain less well‐developed ducts and/or intracytoplasmic lumina 1 . Moreover, ulceration and necrosis (diffuse or comedo‐necrosis) can be found in the histological preparation 1,31,60 . Similar to Robson et al, the presence of necrosis did not have a prognostic relevance in our study 1 .…”

“…The remaining 116 EPC cases of the head and neck from 90 studies were included in the meta‐analysis. The studies consist of 77 single case reports 7‐14,21,25‐93 and 13 case series with an average of three cases 20,23,24,94‐103 . Additionally, four EPC cases of the University Hospital of the Medical University of Vienna and Evangelical Hospital Vienna could be included in the meta‐analysis.…”