Malignant Lymphomas: Classification, Prognosis, and Treatment

Hodgkin's Disease, Autoimmunity, and the Thymus

“…The upper limit of normal of the serum gamma-globulin in this laboratory is 1.33 g./100 ml. Inactive for more than two years Generalized disease (Grade III, Hilton and Sutton, 1962 Clinical.-There was no convincing evidence of autoimmune disease among these 39 cases of Hodgkin's disease. One woman of 22 with a raised serum gamma-globulin had had previous thyrotoxicosis and partial thyroidectomy of a nodular gland.…”

“…The histology of the gland sections had all been carefully reviewed and only those showing typical features of the disease were included (Hilton and Sutton, 1962).…”

Vinblastine Sulphate Treatment of Malignant Lymphomas

“…Firstly, all treatment is only palliative. Secondly, there is a variable natural history with resulting scatter of survival times (Hilton and Sutton 1962). Thirdly, most patients receive a combination of treatment, that is, surgery, radiotherapy and chemotherapy, making an evaluation of any one method difficult.…”