Malignant neoplastic disorders following long-term immunosuppression after orthotopic heart transplantation

Heart Transplantation: Outcome

“…In one series malignancies developed in 10.38% patients. Most common cancers were skin tumours (23.2%), pulmonary neoplasm (15.9%) and urologic tumours (25.4%) (7). In spite of a high level of functional capacity at follow up, only a minority of patients return to work : in our series less than 10%.…”

Adverse Effects of Immunosuppression in Pediatric Solid Organ Transplantation

“…[23] The overall incidence of malignancies following solid organ transplantation is reported to range from 4% to 18%. [24] The most common types of cancers reported include skin carcinomas, anogential carcinomas, Kaposi's sarcoma, and lymphomas, including non-Hodgkin's lymphoma and post-transplant lymphoproliferative disorders (PTLD). Non-skin malignancies occur at a higher rate in pediatric transplant recipients than in adult transplant recipients, with a relative risk (RR) of 1.62 in children.…”

Low incidence of malignancy in heart-transplant recipients in Taiwan: an update and comparison with kidney-transplant recipients

“…The incidence of Kaposi's sarcoma after heart transplantation varied from 0.63% to 11%. Among the solid-organ malignancies after heart transplantation, lung cancer was particularly common, accounting for up to 50% of cases [10][11][12][13][14][15][16][17][18][19]. In this study, most patients had induction therapy with antithymocyte globulins and triple maintenance immunosuppression.…”

“…One patient had double cancers affecting liver and urinary bladder. Lung cancer was the main cause of solidorgan malignancies after heart transplantation in the Western series [10][11][12][13][14][15][16][17][18][19]. However, only one of our patients had lung cancer after transplantation.…”