2004
DOI: 10.1055/s-2004-828705
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Malignant Peripheral Nerve Sheath Tumor of the Orbit: Case Report and Literature Review

Abstract: A 68-year-old woman with progressive visual loss and exophthalmos in her right eye had been operated on for a mass in her right calf 3 years earlier.Imaging showed a huge mass invading the orbital structures and temporal pole. The presumptive diagnosis was a malignant orbital tumor. The tumor was resected totally and eroded tissues such as the lateral rectus muscle and dural compartments were repaired. The histological diagnosis was a malignant peripheral nerve sheath tumor (MPNST). The patient recovered uneve… Show more

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Cited by 33 publications
(16 citation statements)
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“…Soft-tissue sarcomas, including MPNST, are typically reported as locally recurrent, rather than metastatic, and tend to occur in middleaged to older dogs [48]. MPNSTs involving the face are rare and cases associated with the eye have been scant in the veterinary literature [311]. Therefore, the purpose of this case report is to present a canine patient of MPNST that occurred within the orbit and in whom surgical excision was feasible and to describe the histopathological characteristics of canine MPNST.…”
mentioning
confidence: 99%
“…Soft-tissue sarcomas, including MPNST, are typically reported as locally recurrent, rather than metastatic, and tend to occur in middleaged to older dogs [48]. MPNSTs involving the face are rare and cases associated with the eye have been scant in the veterinary literature [311]. Therefore, the purpose of this case report is to present a canine patient of MPNST that occurred within the orbit and in whom surgical excision was feasible and to describe the histopathological characteristics of canine MPNST.…”
mentioning
confidence: 99%
“…The prognosis of MPNST is associated with the tumor's size, location, biological behaviour and history of radiation exposure (26). MPNST can metastasize to the adjacent tissues or distant organs, including the lungs and bones; therefore, the 5-year survival rate is <20%, and 50% of patients experience recurrence (27).…”
Section: Discussionmentioning
confidence: 99%
“…Ці пухлини є саркомами, і час-то тяжко віддеференціювати їх тканинне походження. Пацієнти з НФ-1 мають 10% довічний ризик розвитку злоякісних пухлин периферичних нервів, що найбільш часто виникають із плексиформних нейрофібром [5]. Клінічні і рентгенологічні ознаки злоякісних пухлин практично не відрізняються від доброякісних.…”
Section: результатиunclassified