Mammography as a Screening Tool for Coronary Artery Disease

Dale, Paul S.; Mascarhenas, Christopher; Richards, Michael; Mackie, Gavin C.

doi:10.1016/j.jss.2007.08.022

Cited by 37 publications

(22 citation statements)

References 11 publications

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“…Advancing age (OR 1.1), hypertension (OR 10) and positive CAD on angiography (OR 10.8) was found significantly associated with 12 761 women over the age 40 who attended multiphasic health check ups that included mammography (8). IMAC prevalence was low (3%) compared with other studies (2,6,10,21). This could be explained by low prevalence of CAD and its risk factors among the study population which consisted of generally healthy check up patients.…”

Section: Discussioncontrasting

confidence: 55%

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The association of intramammarian arterial calcifications detected on mammography with coronary artery disease and its risk factors

Lü

Öztürk

et al. 2012

Journal of the Belgian Society of Radiology

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Aim of the study: To evaluate the association of intramammarian arterial calcifications seen on mammography with coronary artery disease and its risk factors and to discuss intramammarian arterial calcifications value as a predictor of coronary artery disease. Material and methods: Mammography was performed on 55 women over 40 years of age who have undergone coronary angiography and have not had a mammography in the past year. Coronary angiography results, coronary artery disease risk factors and intramammarian arterial calcifications are evaluated. Results: The prevalance of intramammarian arterial calcifications was 41.8%. A significant relationship between intramammarian arterial calcifications and coronary artery disease was indicated (OR 10,8, 95% CI 3,02-38,59). The positive predictive value and negative predictive value of intramammarian arterial calcifications for coronary artery disease was 78.3% and 75% respectively. Also advancing age was found relevant with these calcifications (OR 1,15, 95% CI 1,05-1,25). Conclusion:The results support the present literature and suggest that mammography, already widely in use as a screening tool among women over 40, may be used simultaneously in coronary artery disease risk assessment. These results should be confirmed by further larger group controlled studies.

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Section: Discussioncontrasting

confidence: 55%

“…Coronary artery disease (CAD) and cancer are the leading causes of female mortality and morbidity, especially in western countries (1,2). Breast cancer is among the most common deaths caused by cancer.…”

mentioning

confidence: 99%

The association of intramammarian arterial calcifications detected on mammography with coronary artery disease and its risk factors

Lü

Öztürk

et al. 2012

Journal of the Belgian Society of Radiology

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“…11,14 Obstructive CAD was generally defined as ≥50% coronary artery stenosis, except by Sarrafzadegann et al, 16 who used ≥50% stenosis in left main coronary artery and/or ≥75% stenosis in other epicardial arteries as the definition of obstructive CAD. There was 1 prospective cohort study, 7 2 retrospective cohort studies, 8,9 9 case-control studies with CAD, 10–18 1 case-control study with BAC, 19 and 7 cross-sectional (prevalence) studies. 20–25 Table 1 and Figures 2–4 show crude and adjusted ORs calculated from data extracted from each study.…”

Section: Resultsmentioning

confidence: 99%

“…2; Table 1). One case-control study 17 used angiographically documented CAD (obstructive plus nonobstructive) or history of at least one episode of acute myocardial infarction as the definition of the case, and another study 18 used only angiographically documented CAD (obstructive plus nonobstructive) as the definition of case. Both studies showed a statistically significant relation between BAC and CAD.…”

Section: Resultsmentioning

confidence: 99%

Mammographically Detectable Breast Arterial Calcification and Atherosclerosis

Shah

Chainani

Delafontaine

et al. 2014

Cardiology in Review

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Breast arterial calcification (BAC), observed as an incidental finding on screening mammograms, represents degenerative calcific changes occurring in the mammary arteries, with increasing age. The aim of this review is to discuss relevant literature examining relation between BAC and atherosclerosis. After a thorough literature search, in OVID and PubMed, 199 studies were identified, of which 25 were relevant to our review. Data were abstracted from each study and statistical analysis was done, including calculation of odds ratios and construction of forest plots. A total of 35,542 patients were enrolled across 25 studies looking at an association between BAC and coronary artery disease, cardiovascular disease, stroke, cerebral artery disease, carotid and peripheral artery diseases, and coronary artery calcification. A majority of the studies showed a statistically significant relation between BAC and presence of coronary artery disease cardiovascular disease and associated mortality. Sensitivity of BAC in predicting cardiovascular events was low, but specificity was high. BAC was predictive of incident and prevalent stroke but not mortality of stroke. Similarly, BAC was predictive of cerebral, carotid, and peripheral artery diseases. The role of BAC as a surrogate marker of coronary and systemic atherosclerosis is currently uncertain. Its role may be further elucidated by more large-scale prospective studies and clinical experience.

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“…More significantly, women with CAD had a considerably higher incidence of BAC compared with age-matched women with no known CAD (P < 0.0001) The odds ratio of having CAD when BAC was present compared with having CAC when BAC is not present was 6.2% (95% confidence interval 4.3-8.8). This study indicates mammography may be a useful screening tool to identify women at risk for CAD [12].…”

Section: Discussionmentioning

confidence: 76%