Management and prognosis of endometrioid borderline tumors of the ovary

Uzan, Catherine; Berretta, Roberto; Rolla, Martino; Gouy, Sébastien; Fauvet, R.; Daraı̈, Émile; Duvillard, P.; Morice, Philippe

doi:10.1016/j.suronc.2012.02.002

Cited by 28 publications

(48 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Over the past two decades, considerable work has been performed to investigate the clinicopathologic features of serous and mucinous BOTs, as well as the oncological and fertility outcomes of patients with BOTs [ 3 – 5 ]. However, due to its rare incidence, endometrioid BOTs (EBOTs), the third most common BOT, have been poorly studied [ 6 ]. Most studies on EBOTs have focused mainly on the pathological characteristics and included only brief descriptions of management and follow-up [ 6 – 10 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, due to its rare incidence, endometrioid BOTs (EBOTs), the third most common BOT, have been poorly studied [ 6 ]. Most studies on EBOTs have focused mainly on the pathological characteristics and included only brief descriptions of management and follow-up [ 6 – 10 ]. Additionally, only a few cases that were treated with conservative surgery have been reported; therefore, the fertility outcomes of these patients are unknown [ 6 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Risk of synchronous endometrial disorders in women with endometrioid borderline tumors of the ovary

et al. 2018

View full text Add to dashboard Cite

BackgroundSynchronous endometrial disorders have been poorly studied in women with endometrioid borderline ovarian tumors (EBOT). The aims of this study were to investigate the risk of endometrial disorders among women with EBOT and associated factors, as well as their oncological and fertility outcomes.ResultsThis retrospective study included 33 women with EBOT. Their mean age was 41.9 years, and endometria were evaluated in 25 of these patients. The prevalence of synchronous endometrial disorders was 52.0% (n = 13/25) and this incidence was 41.4% (n = 46/111) after systematic analysis. Univariable analysis showed that EBOT patients who were younger, nulliparous, and had experienced abnormal vaginal bleeding were more likely to have synchronous endometrial disorders. The median follow-up was 54 months (range: 14-250 months), and three patients (10.3%) developed recurrences. No deaths due to EBOT were recorded. Among the nine nulliparous women treated conservatively who were attempting to conceive, only one (11.1%) pregnancy resulted in a live birth.ConclusionsSynchronous endometrial disorders are common in women with EBOT, especially in those who are younger, nulliparous, and have experienced abnormal vaginal bleeding. Thus, endometrial sampling should be performed in women with EBOT undergoing conservative surgery, and a hysterectomy should be performed in cases requiring radical treatment.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Risk of synchronous endometrial disorders in women with endometrioid borderline tumors of the ovary

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The majority of the reported cases are confined to a unilateral ovary, and metastasis and recurrence are rare ( Table 3 ). 3 – 6 …”

Section: Discussionmentioning

confidence: 99%

“…Among 122 EBT cases, 56 (46%), including 4 cases from our institution, were associated with endometriosis ( Table 3 ). 3 – 6 Among 43 patients who underwent hysterectomy, endometrial lesions including endometrial polyps, endometrial hyperplasia, and endometrial cancer were diagnosed in 23 patients (53%) ( Table 3 ). In the four patients from our institution, one had endometrial polyp and two had early-stage endometrial cancer ( Table 1 ).…”

Section: Discussionmentioning

confidence: 99%

Four cases of endometrioid borderline ovarian tumour: case reports and literature review

et al. 2018

View full text Add to dashboard Cite

Endometrioid borderline tumours (EBTs) of the ovary are uncommon tumours of low malignant potential. They consist of atypical endometrioid cells lacking destructive stromal invasion. As the prognosis of EBT is excellent, excessive treatment should be avoided and preoperative diagnosis is important. Here we report four cases of ovarian EBTs along with imaging findings and a review of literature. The average patient age was 52 years. They presented with abdominal discomfort or abnormal vaginal bleeding. The final diagnoses for all four cases were EBT Stage IA with endometriosis. Pathologically, one case was an adenofibromatous type tumour, and three cases were intracystic type tumours. Two patients had concurrent endometrial cancer. MRI of the tumours showed enhanced solid components. The intracystic type tumours presented a dendritic structure in the cyst; fine papillary branches surrounded a low-signal trunk on T2 weighted imaging. Positron emission tomography demonstrated marked fluorodeoxyglucose uptake in the solid component. One case with MRI 3 years before diagnosis indicated that the tumour arose in ovarian endometriotic cyst. EBT cases were difficult to distinguish from malignant ovarian tumours preoperatively. Intraoperative frozen section analysis may aid to determine treatment. Prognoses were excellent. Care should be taken for co-existing endometrial cancer.

show abstract

“…Endometrioid BOT represent an infrequent subset of tumors that can be associated with synchronous endometrioid adenocarcinoma of the uterine corpus. Although most tumors are stage I, and therefore surgical staging is not necessary in most of the cases, uterine curettage is required in cases of uterine preservation [23] .…”

Section: Surgical Stagingmentioning

confidence: 99%

Management of Borderline Ovarian Tumors – state of the art

Vasconcelos

2015

Uterus Ovary

View full text Add to dashboard Cite

Borderline ovarian tumors (BOT) have invited controversy for decades. In the last couple of years research has showed a shift towards less aggressive treatment. This review summarizes the latest studies and therapeutic consequences thereof. Staging procedures are recommended in the setting of serous BOT, but controversial in the setting of mucinous BOT, where they may represent overtreatment. Surgical staging is limited to bilateral salpingo-oophorectomy, peritoneal cytology/biopsies and an omentecomy. Neither a hysterectomy nor lymphadenectomy should be undertaken. Conservative management should consist of a cystectomy or unilateral salpingo-oophrectomy in the setting of serous BOT and unilateral salpingo-oophrectomy in the case of mucinous BOT. Bilateral disease should be treated by bilateral cystectomy whenever possible. At present, there are no data to support the use of adjuvant treatment in any setting of BOT. To cite this article: Ines Vasconcelos. Management of borderline ovarian tumors -state of the art. Uterus Ovary 2015; 2: e885.

show abstract

Management and prognosis of endometrioid borderline tumors of the ovary

Cited by 28 publications

References 6 publications

Risk of synchronous endometrial disorders in women with endometrioid borderline tumors of the ovary

Risk of synchronous endometrial disorders in women with endometrioid borderline tumors of the ovary

Four cases of endometrioid borderline ovarian tumour: case reports and literature review

Management of Borderline Ovarian Tumors – state of the art

Contact Info

Product

Resources

About